Sentences with phrase «scale trial on»

After President Trump took office in 2017, the challenge in Judge Hanen's court had not yet reached a final legal conclusion because there had never been a full - scale trial on the legality of the November 2014 actions by President Obama.

Not exact matches

While the new mid-stage study results from DNDi were impressive (they showed cure rates of 96 % to 97 % even for the sickest patients and those with liver scarring), more late - stage trials will be necessary before the drug is available on a large scale in the developing world.

Some small studies have suggested that synbiotics could provide benefits to a range of other conditions influenced by the gut microbiome as well, including obesity, diabetes, and non-alcoholic fatty liver disease, but larger - scale clinical trials focusing on each of those conditions are needed.

ZURICH (Reuters)- Roche's Tecentriq immuno - oncology drug failed a late - stage follow - up trial against advanced bladder cancer, the Swiss drugmaker said on Wednesday, raising questions about whether regulators could scale back their approval of the medicine.

Competitive advantages, including scale, existing patents on blockbuster drugs (such as Enbrel), broad geographical and product diversification, R&D, and a strong pipeline of drugs (16 compounds in Phase III trials) give this firm the strengths it needs to fight risks like competition, litigation, and regulation.

Second, and more important, these trials exhibit in exaggerated form what is also happening on a smaller scale throughout the criminal justice system: «Though no avalanche has occurred,» Wilson observes, «the courts are having difficulty keeping their footing on a slope that has become increasingly slippery.»

This is trial and error spending on an unprecedented scale — christ, if they can't put a decent team on the field now then Man U should pack it in and call it a day.

Despite aromatherapy's long history of use, there is still a lack of large - scale clinical trials exploring the effects of aromatherapy on anxiety.

By late 2012, it adds, «the department had largely stopped developing systems for national roll - out and concentrated its efforts on preparing short - term solutions for the pathfinder» (the small scale trial of the system).

And in several large - scale pharmaceutical trials, drugs specifically designed to elevate HDL had no effect on heart disease risk.

As Scientific American reported earlier this year, more than half of the current cancer clinical trials do incorporate some form of immunotherapy but still oncologists are often only in the early stages of understanding how to use such treatment on a larger scale.

That year, Targacept reported that in phase II trials with an approved antidepressant, TC - 5214 had few side effects and produced a six - point improvement on the Hamilton rating scale for depression.

Dawe and his team are optimistic that they will make progress by the end of their initial 18 - month project period, but whether their trials yield anything that can be scaled up on a meaningful level remains to be seen.

Also in this issue, how single - person medical experiments, alternatives to big clinical trials, are leading to breakthroughs on a small scale.

The trial found that on a 13 - point scale, women who took the drug sold as Diclectin in Canada (Diclegis in the United States) reported symptom reductions that were 0.7 points greater than women who took a placebo.

Roughly 250,000 of the wasps (Anagyrus lopezi) landed in Thailand's northeastern province of Khon Kaen on July 17 — after initial small - scale field trials proved effective.

The results from the latest trials, in 2014, focused on three endpoints: sexual function index (where women answered questions about sexual experience and rated levels of sexual desire on a scale of one to five over the last 28 days), satisfied sexual events, and distress felt from a low libido.

These early trials tipped clinicians to flibanserin's more prominent role in sexual health, as female subjects had higher scores on the Arizona Sexual Experience Scale, a survey that asks participants to rate their satisfaction on a variety of sexual health topics, like how often participants felt sexual desire and how intense that desire was.

To journey safely from this universe to another — to investigate the various options and do some trial runs — an advanced civilization will need to be able to harness energy on a scale that dwarfs anything imaginable by today's standards.

When projects on the scale of a nuclear power station or THORP are concerned, or the release of genetically modified organisms into the environment, to give another example, it is not possible to model them fully in the laboratory using traditional trial - and - error methodology.

We would like to consider doing it on a larger scale, maybe having several universities studying patients with different diagnostic categories to see how a controlled psychotherapy trial produces physical brain changes as a result of treatment.

Vaccine trials started last week, and initial observations are promising, but Donnelly and her team warn that it will take many months to scale up production sufficiently to start having an effect on the current epidemic.

Researchers from the United Kingdom undertook an open randomized controlled trial to determine if autoinflation with a nasal balloon could be used on a large scale to benefit children in primary care settings.

The ONTRAC trial assessed ADHD symptom severity using a parent rating scale, and measured cognitive performance on tests of attention, response inhibition and working memory.

In 2002, the research team for TRIGR (Trial to Reduce IDDM in the Genetically at Risk), led in the U.S. by principal investigator Dorothy Becker, M.D., professor of pediatrics at Children's Hospital and the University of Pittsburgh School of Medicine, embarked on a large - scale study of 2,159 infants with a family member affected by type 1 diabetes and with genetic risk for type 1 diabetes to find out whether delaying the exposure to complex foreign proteins such as cow's milk proteins would decrease the risk of diabetes.

«At their baseline, before patients started treatment, patients in both groups were on the lower end of the scale, meaning they reported lower amounts of fatigue,» said the trial's principal investigator Neha Vapiwala, MD, an associate professor of Radiation Oncology.

They will perform preliminary studies to prepare for large - scale testing, conduct related studies to support specific trials, provide mentoring for junior faculty, and help recruit appropriate patients to Network trials, especially those expected to have a significant positive impact on cancer treatment.

Though the field trials have been relatively small so far, the operationally similar Sterile Insect Technique has been successfully used to eliminate pests on various scales up to continent - wide.

They noted that the present findings warrant a confirmatory clinical trial for SMA rTMS on PD, undertaken on a larger scale.

All eyes are on a new BCG - based TB vaccine, VPM1002, which has shown promise in animal and small - scale human trials.

The study was not a clinical trial, and the tailored approach may be difficult to replicate on a larger scale, Hendrix noted.

Several large scale and highly publicized meta - analyses have been done on all trials to date regarding saturated fat.

As expected, measurements of fatigue, soreness, and exertion on a Likert scale revealed significant differences from pre to post during each exercise trial.

Measurements of fatigue, soreness, and exertion on a Likert scale revealed significant differences from pre to post during each exercise trial.

Frodo and Sam's journey had reached a point where the trials they had survived were balanced by the scale of what was still facing them, enabling the film to stand on its own.

It is this solitary moment of euphoric release in Tarantino's constructed jungle of human viciousness that is ultimately the most heartbreaking, encapsulating life's little triumphs in a sea of overwhelming trials on a truly epic scale.

The EEF will recruit 920 primary schools, over 48,000 pupils, to trial the projects on a larger scale.

The EEF will now discuss with the Switch - on team options for developing and testing an alternative model for scaling the intervention that can be delivered in many schools, but with the same positive effects of the smaller trial.

These time demands should also decrease as blended learning scales beyond pilot classrooms and piloting teachers are able to train their colleagues on the best practices they had to figure out through trial and error.

New evidence has been collected from publicly funded voucher programs in Florida and Cleveland; new findings from randomized field trials conducted in New York City, Dayton, Charlotte, and Washington, D.C., are now available; and a growing body of evidence collected abroad provides a comparative perspective on the probable effects of large - scale choice initiatives.

The results of a large - scale randomized controlled trial of Conjoint Behavioral Consultation (CBC) on student outcomes and teacher - parent relationships in rural schools are presented.

Mathematics Learned by Young Children in an Intervention Based on Learning Trajectories: A Large - Scale Cluster Randomized Trial

As to goal two, I'll need to collect further data before I can report back on whether a trial of this scale, duration and impact had the desired effect.

Competitive advantages, including scale, existing patents on blockbuster drugs (such as Enbrel), broad geographical and product diversification, R&D, and a strong pipeline of drugs (16 compounds in Phase III trials) give this firm the strengths it needs to fight risks like competition, litigation, and regulation.

However, it does not end there as numerous activities are around every corner and straight such as competing in time trials from a few seconds in length through a single street for around 5 seconds or an entire route taking around 2 minutes in attempt after attempt to beat offline times or times set by players on a global scale for times and show times in road rules, alongside 400 gates and 120 billboards to smash through as well as 50 jumps to land and more besides.

AN artist known for his work on the Lockerbie trial and scale models of Edinburgh's churches has been shortlisted for the GBP25, 000 Turner Prize.

Given some trial you mentioned had some data on how much additional carbon was sequestered it should be possible to do a calculation on whats possible at larger scale and over what time periods

After settling on silica, she scaled up her experiments with trials on ice in California's Sierra Nevada and on Canada's Miquelon Lake.

Trial and scale radically disruptive organizational structures, systems and technologies to deliver on their respective missions.

[44] The trial judge properly placed the prior consistent statement on the scale in assessing the credibility of the complainant's in - court testimony by considering the circumstances in which she made her initial complaint to Constable Flint.