Sentences with phrase «scale trials in»

Previous studies, including large - scale trials in China, have shown that cruciferous vegetables that have a high concentration of sulforaphane — such as broccoli, cabbage and garden cress — help mitigate the effects of environmental carcinogens.

This vaccine has been at the heart of a controversy in the US after Congress awarded the defence department $ 20 million to test it in large - scale trials in America as an immune therapy for HIV - positive people.

It worked well in a pilot test in Washington, D.C., and an international consortium has been organized for a large - scale trial in Costa Rica.

The academic explains the approach used in the UK pilot study grew out of an initial, small - scale trial in Melbourne involving 30 teachers and students with disabilities.

A small - scale trial in the UK found that using OneNote's Learning Tools had a positive effect on the learning experience for students with dyslexia.

What started as a small scale trial in the NT has spread; today there are services in the NT (now funded by the NT Government and private local donations), in the Hunter region in NSW (delivered in a partnership between beyondblue, Movember, Hunter Primary Care, Calvary Mater Hospital, the Hunter Institute of Mental Health and Relationships Australia), and the ACT (funded by the ACT Government and delivered in partnership with Woden Community Service).

Not exact matches

While the new mid-stage study results from DNDi were impressive (they showed cure rates of 96 % to 97 % even for the sickest patients and those with liver scarring), more late - stage trials will be necessary before the drug is available on a large scale in the developing world.

Just this month, as part of the first large - scale clinical trial of its kind, researchers working in rural India found that newborns who were given a synbiotic were at a substantially lower risk of developing sepsis, a potentially fatal condition characterized by severe infection.

Grail, a year - old, Menlo Park, Ca. - based early cancer screening startup that spun out of the DNA - sequencing giant Illumina is reportedly looking to raise up to $ 1.7 billion in fresh funding to launch a large - scale clinical trial.

The results, which mirror those of similar, small - scale studies of the illegal drug in recent years, come as MDMA is about to enter larger, Phase 3 trials this summer.

After President Trump took office in 2017, the challenge in Judge Hanen's court had not yet reached a final legal conclusion because there had never been a full - scale trial on the legality of the November 2014 actions by President Obama.

The success of this month's NASA - UTM TCL3 trials is further proof that strong cooperation between private and public industry players is essential to enabling safe high - scale drone operations and is already happening in the United States and worldwide.

Competitive advantages, including scale, existing patents on blockbuster drugs (such as Enbrel), broad geographical and product diversification, R&D, and a strong pipeline of drugs (16 compounds in Phase III trials) give this firm the strengths it needs to fight risks like competition, litigation, and regulation.

Second, and more important, these trials exhibit in exaggerated form what is also happening on a smaller scale throughout the criminal justice system: «Though no avalanche has occurred,» Wilson observes, «the courts are having difficulty keeping their footing on a slope that has become increasingly slippery.»

The pilot equipment, which is capable of handling multiple trials in small batches and applications, can be scaled up with a high - degree of repeatability in industrial set - up.

He contributes to other large - scale clinical trials including SAVE (evaluating whether treatment of obstructive sleep apnoea with continuous positive airways pressure can reduce the incidence of serious CV events in patients with established CVD), and CREDENCE, a randomised, double - blind, placebo - controlled trial assessing whether canagliflozin can slow the progression of diabetic nephropathy in patients with type 2 diabetes.

This is trial and error spending on an unprecedented scale — christ, if they can't put a decent team on the field now then Man U should pack it in and call it a day.

The third program, developed in Australia and employed in a large - scale trial at the University of South Carolina, is called the Triple P - Positive Parenting Program.

Conducted by Ron Prinz of the University of South Carolina, this first large - scale American trial of Triple P directly addressed, and affirmed, the success of the program in reducing substantiated child maltreatment, out - of - home placements of maltreated children, and maltreatment injuries.

«Protein in breast milk reduces infection risk in premature infants: Study shows need for large - scale trial of lactoferrin's role in immune system development.»

The parliamentary assembly of the European Court has called the scale of GCHQ's spying «stunning» and found it in violation of rights to privacy, free expression and a fair trial.

And in several large - scale pharmaceutical trials, drugs specifically designed to elevate HDL had no effect on heart disease risk.

In light of the results, the CNIO Breast Cancer Clinical Research Unit has already launched a large - scale Phase II Clinical Trial to validate the results in a large group of patientIn light of the results, the CNIO Breast Cancer Clinical Research Unit has already launched a large - scale Phase II Clinical Trial to validate the results in a large group of patientin a large group of patients.

The drug is undergoing testing at a 3 milligram (mg) dose for long - term weight management as part of the SCALE ™ (Satiety and Clinical Adiposity — Liraglutide Evidence in Nondiabetic and Diabetic Subjects) Obesity and Prediabetes trial.

This year, Rocke hopes to conduct larger - scale field trials to determine the levels of immunity required for success in a mass vaccination.

The SCALE Obesity and Prediabetes trial is continuing for two more years for the prediabetic subjects in arm 2.

Previous clinical trials of creatine in symptomatic HD patients have been limited in scale, involved daily doses of 10 grams or less, and did not provide evidence of potential efficacy.

The drug is not approved for weight management, according to its manufacturer, Denmark - based Novo Nordisk, which sponsored this study, called the SCALE ™ (Satiety and Clinical Adiposity - Liraglutide Evidence in Nondiabetic and Diabetic Subjects) Obesity and Prediabetes trial.

As Scientific American reported earlier this year, more than half of the current cancer clinical trials do incorporate some form of immunotherapy but still oncologists are often only in the early stages of understanding how to use such treatment on a larger scale.

That's because a trial like this one is almost without precedent in modern medical research: It involves giving children a vaccine that is almost certain not to benefit them, and that might harm them, all to protect other children from an unlikely scenario — a large - scale anthrax attack.

That year, Targacept reported that in phase II trials with an approved antidepressant, TC - 5214 had few side effects and produced a six - point improvement on the Hamilton rating scale for depression.

And scientists who conduct human challenge studies, which typically involve a few dozen participants, say they have critical benefits: In addition to saving time and money, they can reveal harm caused by a potential drug or vaccine before it enters large - scale human efficacy trials.

«Given a city like Philadelphia's prior experience with gun violence, the 29 percent reduction in crime reported in this trial could translate into hundreds of fewer shootings each year if the vacant land interventions tested here were scaled beyond just the locations of the study,» said Branas.

Also in this issue, how single - person medical experiments, alternatives to big clinical trials, are leading to breakthroughs on a small scale.

«At the same time, small - scale trials have shown that consuming antioxidant - rich foods like virgin olive oil, tomatoes and berries improved HDL function in humans.

But vaccines that only contained HIV's surface protein looked lackluster in animal and test tube studies, and then proved worthless in large - scale clinical trials.

Researchers recommend large - scale clinical trials to confirm that nighttime fasting results in favorable changes to biomarkers of glycemic control and breast cancer risk.

It was originally designed to advance to a Phase 3 trial among 28,000 volunteers but was scaled back because the decline in new Ebola cases made it impossible to conduct the larger study.

In 2013, Dr. Schwartz and his colleagues launched the first large - scale, Phase II, randomized trial of selumetinib.

Becoming compliant with the proposed ruling could, according to one HHS official, drive up the cost of doing large - scale trials or surveys because of the extra work involved in ensuring that projects meet the standards required.

The trial found that on a 13 - point scale, women who took the drug sold as Diclectin in Canada (Diclegis in the United States) reported symptom reductions that were 0.7 points greater than women who took a placebo.

Roughly 250,000 of the wasps (Anagyrus lopezi) landed in Thailand's northeastern province of Khon Kaen on July 17 — after initial small - scale field trials proved effective.

Wolfe acknowledges, however, that we won't know what the long - term safety issues are until a large - scale human trial is conducted, which researchers hope to begin in the next three years.

The results from the latest trials, in 2014, focused on three endpoints: sexual function index (where women answered questions about sexual experience and rated levels of sexual desire on a scale of one to five over the last 28 days), satisfied sexual events, and distress felt from a low libido.

These early trials tipped clinicians to flibanserin's more prominent role in sexual health, as female subjects had higher scores on the Arizona Sexual Experience Scale, a survey that asks participants to rate their satisfaction on a variety of sexual health topics, like how often participants felt sexual desire and how intense that desire was.

«However, large - scale, randomized clinical trials will provide more definitive evidence regarding these risks in the coming years.»

In another small - scale trial for multiple sclerosis, treatment appeared to reverse the disease's progression and its associated disability, a further historic first.

We also have a large - scale biologics manufacturing facility in Rensselaer, New York, where we produce commercial and investigational products for clinical trials, and a satellite office in Basking Ridge, New Jersey.

The controversy came to a head in March when the National Institutes of Health issued a notice of a competition soliciting participation in a large - scale clinical trial to evaluate the effectiveness of fetal surgery as a treatment for spina bifida.

One malaria vaccine is in large - scale trials.