In the real brain, maintaining a proper balance in neural network activity is important; disruptions in it appear to foster disorders such as epilepsy, and
perhaps schizophrenia and autism.
Disturbances in the functioning of this network, as well as various kind of infection and other triggers of a pregnant woman's immune response, have been linked to development of psychiatric illnesses, such
as schizophrenia and autism spectrum disorders.
REYKJAVIK, Iceland, Dec. 18, 2013 — deCODE genetics, a global leader in analyzing and understanding the human genome, reported today in the journal Nature that mutations associated with an increased risk
of schizophrenia and autism also affect cognition in individuals without the disease or intellectual disability.
REYKJAVIK, Iceland, Dec. 18, 2013 - deCODE genetics, a global leader in analyzing and understanding the human genome, reported today in the journal Nature that mutations associated with an increased risk of
schizophrenia and autism also affect cognition in individuals...
Professor John McGrath, a psychiatrist and epidemiologist from the Queensland Brain Institute at the University of Queensland is one of a growing number of researchers investigating a link between older fathers and neurological conditions
including schizophrenia and autism in their children.
The overlap in heritability attributable to common genetic variation was about 15 percent between schizophrenia and bipolar disorder, about 10 percent between bipolar disorder and depression, about 9 percent between schizophrenia and depression, and about 3 percent
between schizophrenia and autism.
Feng and colleagues Robert Desimone, director of the McGovern Institute, and MIT professor Feng Zhang, a co-inventor of the CRISPR technology (pending U.S. Patent and Trademark Office investigation and ruling), are working with Chinese researchers to develop CRISPR - modified macaques — a monkey found in many Old World environments — to model
human schizophrenia and autism.
Working with this hypothesis, the researchers conducted a statistical analysis of the CX3CR1 gene in over 7000
schizophrenia and autism patients and healthy subjects, finding one mutant candidate, a single amino acid switch from alanine to threonine, as a candidate marker for prediction.
Even though a biomarker shared
by schizophrenia and autism might not reveal anything specific to autism, he adds, it might highlight a neural process that is central to social cognition, and that might be altered in several conditions, including autism.
Last week at the 23rd International Conference on Subterranean Biology in Fayetteville, Arkansas, he demonstrated how drugs that help people with
schizophrenia and autism similarly affect the fish.
«Because big genetic studies have been done
on schizophrenia and autism and other diseases, you can calculate someone's risks of developing those diseases from their genetic information and you can see if it's associated with contagious yawning,» she said.
Studies have identified an association between maternal infection and inflammation and preterm birth, in addition to the development of cerebral palsy and neuropsychiatric conditions such
as schizophrenia and autism.
At this special event, Dr. Anthony - Samuel La Mantia, director of the George Washington Institute of Neuroscience, will present highlights from his research on the role of forebrain development and gene regulation in behavioral and psychiatric diseases
including schizophrenia and autism.
I had the pleasure of being introduced to Vanderbilt University psychiatrist Howard Meltzer, whom you quote in the article, and I share his concern about the lack of knowledge — on the part of both the lay public and medical professionals — about this cause of one third or more of noninherited cases
of schizophrenia and autism.
In a separate line of research, Dr. Rudolph and his staff are using chromosome engineering to generate mouse models with copy number variations (deletions and duplications) that are known risk factors
for schizophrenia and autism in humans.
Researchers funded in part by the National Institutes of Health found that the overlap was highest between schizophrenia and bipolar disorder; moderate for bipolar disorder and depression and for ADHD and depression; and low
between schizophrenia and autism.
The molecules produced during gluten digestion include exorphins, which have also been found in the spinal fluid of people
with schizophrenia and autism, and are thought to worsen the symptoms of these neurological diseases.
Back then, it was hypothesised that the A1 beta - casein protein found in the milk of some cows was a risk factor for diabetes, heart disease and possibly also
schizophrenia and autism.
Osaka University researchers show in a multi-institute collaboration that a single amino acid substitution in the protein CX3CR1 may act as predictor for schizophrenia and autism
«Aberrant synapse formation is important in the pathogenesis of
schizophrenia and autism,» says Osaka University Professor Toshihide Yamashita, one of the authors of the study.
A new multi-institutional study by Japanese researchers shows a potential rare gene mutation that could act as a predictor for two neurodevelopmental disorders,
schizophrenia and autism.
The list included
schizophrenia and autism.
Study co-author David Sweatt, a neurobiologist at the University of Alabama at Birmingham, says the finding could provide new targets for treating mental illnesses such as
schizophrenia and the autism - spectrum disorder Rett, conditions in which improper methylation switches off certain genes during development.
Future studies about romantic attachment will focus on using the findings from research such as Young's and Diamond's to develop new treatments for grief associated with partner separation or loss and for disorders that involve social deficits, such as
schizophrenia and autism.
Such disorders, which include epilepsy and, experts theorize,
schizophrenia and autism (SN Online: 7/17/15), can arise when the brain's communication networks develop off - kilter.
Of the many disorders that can afflict the brain,
schizophrenia and autism are among the most inscrutable.
Upper layer neurons are also frequently affected in psychiatric disorders such as
schizophrenia and autism.
Some implicate developmental problems, such as faulty pruning of the connections between neurons, in
both schizophrenia and autism.
Advanced paternal age has been associated with greater risk for psychiatric disorders, such as
schizophrenia and autism.
Now they believe these same molecules, when the system fails, might be involved in conditions as diverse as Alzheimer's, glaucoma,
schizophrenia and autism.
«Some neuropsychiatric disorders, such as
schizophrenia and autism, are characterized by the abnormal development of synaptic connectivity in certain key parts of the brain,» explains Schneggenburger.
Dysfunction of synapses is associated with a host of neuropsychiatric disorders such as epilepsy, addiction,
schizophrenia and autism.
In humans, the cerebellum's extensive connectivity with the rest of the brain suggests it does far more than learn motor skills: it has been shown to have a part in both perception and cognition, with recent work linking cerebellar dysfunction to such complex diseases as
schizophrenia and autism.
The evidence from MRI scans suggests that such Neanderthal - derived genetic variation may affect the way our brains work today — and may hold clues to understanding deficits seen in
schizophrenia and autism - related disorders, say the researchers.
The current challenge is to identify which genes contribute to multifactorial conditions like obesity, heart disease, alcohol dependency,
schizophrenia and autism.
In a final step they also analysed whether any of the enhancers contained genetic changes already linked to a range of disorders including, attention deficit disorder, depression, bipolar disorder,
schizophrenia and autism.
Shreejoy Tripathy (DC» 13), a Ph.D. graduate in neural computation from the Center for the Neural Basis of Cognition's (CNBC), is now a postdoc in the Pavlidis Lab at the University of British Columbia, studying neuropsychiatric disorders such as
schizophrenia and autism.
Through the use of stem cell - based organoids researchers are making big strides in the study of neurodevelopmental diseases such as
schizophrenia and autism.
Being social animals, zebrafish are an interesting model for studying psychiatric disorders that affect social behavior, such as
schizophrenia and autism.
Certain copy number variants (CNVs), one type of mutation, have been previously identified as strong risk factors for
schizophrenia and autism, neuropsychiatric diseases which affect cognition.