C4's involvement might also explain why
schizophrenia arises during the late teens into the 20s.
When Bigger Isn't Better Dudley's findings offer a possible explanation for why
schizophrenia arose in humans in the first place and why it does not seem to occur in other animals.
The serotonin (5 - HT) hypothesis of
schizophrenia arose from early studies on interactions between the hallucinogenic drug LSD (D - lysergic acid diethylamide) and 5 - HT in peripheral systems.
Not exact matches
«This new model speaks to how
schizophrenia could
arise before birth and identifies possible novel drug targets,» said Jerold Chun, a professor and member of the Dorris Neuroscience Center at TSRI who was senior author of the new study.
Such disorders, which include epilepsy and, experts theorize,
schizophrenia and autism (SN Online: 7/17/15), can
arise when the brain's communication networks develop off - kilter.
In layer 2, the density of cartridges
arising from a transcriptionally - unique subset of chandelier cells containing calbindin was nearly 3-fold higher in the
schizophrenia group.
«They might not
arise from the same brain areas, but these observations are of importance in efforts to understand hallucinations that commonly occur in psychiatric disorders such as
schizophrenia,» says Matcheri Keshavan, a psychiatrist at Harvard Medical School.
No single genetic mutation can ever account for the complex range of symptoms that
arise in devastating neuropsychiatric disorders such as
schizophrenia.
According to Andreassen, the study's senior author, some think of
schizophrenia as a «side effect»
arising from advantageous variants in genes that are related to the development of human traits, such as cognitive and language skills, that may have increased risks for developing psychoses.
«Our finding ultimately could have implications for understanding and treating many brain disorders
arising from aberrant hippocampal neurogenesis, including epilepsy,
schizophrenia, depression, and Alzheimer's disease.»