Review: non-steroidal anti-inflammatory drugs may reduce
schizophrenia symptom severity in the short term when added to antipsychotics
Not exact matches
Brain activation and
severity of
symptoms in
schizophrenia patients: Red areas represent regions related to the
severity of speech fluency in
schizophrenia.
Led by Brenda Penninx, PhD, of the VU University Medical Center in Amsterdam, the Netherlands, the study found that patients with an early age at onset and higher
symptom severity have an increased genetic risk for MDD, bipolar disorder and
schizophrenia.
In this study, the researchers compared the
severity of negative
symptoms and proline levels in 95 hospitalized
schizophrenia patients with variants of the COMT gene.
Decreased vagal tone in patients with
schizophrenia is significantly correlated with
symptom severity.32, 33)
Negative
symptoms and clinical
severity were assessed using five items from the
schizophrenia Postive and Negative Syndrome Scale (PANSS) negative
symptoms subscale (blunted affect, emotional withdrawal, poor rapport, social withdrawal and verbal fluency).
Design: Patients with chronic
schizophrenia were randomly allocated, stratified according to
severity of
symptoms and sex, to intensive cognitive behaviour therapy and routine care, supportive counselling and routine care, and routine care alone.
Prognostic factors
Severity of positive and negative
symptoms (schedules for positive and negative
symptoms); course of illness over the past 2 years; level of functioning (Global Assessment of Functioning scale (GAF)-RRB-; premorbid functioning (Premorbid Adjustment scale); duration of untreated psychosis (interview for retrospective assessment of onset of
schizophrenia); days of hospitalisation; number of contacts with psychiatric services; number of days in supported housing.