Not exact matches
All the
animals completed a series of cognitive
tests at the start of the study and were injected with a substance that allows
scientists to track changes in their brain structures.
Scientists have linked low doses of BPA to obesity, diabetes, thyroid disease, breast cancer, prostate cancer and other illnesses in lab
tests on
animals.
So why are UK
scientists still conducting antiquated experiments on
animals that have, for decades, proved ineffective, while modern non-animal
testing methods have advanced by leaps and bounds?
Forward - thinking
scientists, many with funding from PETA and its international affiliates, are developing methods for studying diseases and
testing products that don't require the use of
animals and are actually relevant to human health.
In medicine today, physician -
scientists and basic
scientists supplement support for their research by applying their expertise part time to develop and
test commercial products.1 In my own field, vision science, university - based researchers obtain additional funding through clinical and electrophysiologic studies, pathology, imaging, biochemistry, and
animal model development performed for pharmaceutical and instrument companies.
Scientists are forced either to experiment on whole
animals, which is expensive, raises ethical issues and may not predict effects in humans, or to perform
tests on microscopic human cells found in tissue cultures, which have been altered to live forever and bear little relation to actual living, breathing people.
Yet governments continue to mandate
animal tests, despite the lack of a formal demonstration of fitness for purpose, and a growing global realisation among
scientists that
animal toxicity
tests are inadequate and must be replaced.
The unexpected idea has been
tested only in cells and
animals so far, but some
scientists are already considering whether lowering oxygen levels might treat certain rare but deadly conditions.
The
scientists tested the new compound using a mouse model of TB and found that substituting R207910 for one of three antibiotics in a treatment cocktail significantly reduced the time required to clear the
animals» lungs of bacteria.
Safety regulations prohibit introducing these mutations to actual H7N9 viruses, limiting
scientists» ability to
test their effects in
animals.
But aided by new
tests that allow
animals to show their smarts unhobbled by human preconception,
scientists have discovered that there may be more similarities between human and
animal intelligence than differences.
Prompted by the recent Zika virus outbreaks in Latin America and some parts of the United States,
scientists around the world have been racing to develop candidate vaccines, and already several have been
tested in
animals.
However,
scientists say the
tests may have exaggerated the impact by subjecting
animals to doses of CO2 far higher than they would sense during careful gas disposal.
In a verdict that U.K.
scientists see as a turning point in efforts to protect
animal researchers against illegal attacks, a British court yesterday convicted four people of conspiring to blackmail companies that supply an
animal testing laboratory.
The 5 - year project, called Tierversuche verstehen (Understanding
animal testing), is centered around a website providing
scientists» testimonials and background information.
But
scientists now report they have developed gels that, in
animal tests, can be injected into the heart to shore up weakened areas and prevent heart failure.
Kasting, who is collaborating with Arne Naegel and Gabriel Wittum from Goethe University in Frankfurt, Germany, for this research, says mathematical modeling allows
scientists to
test chemical compounds virtually, in place of human or
animal testing.
The
scientists checked fecal swabs taken from dozens of
animals in Dong Thap province and found what the virologist calls «remarkably high» incidence of the virus: Nearly 60 % of the
animal samples
tested positive.
Scientists said the platform is part of LLNL's broader vision for countering emerging and existing threats, allows them to study the networks formed among various regions of the brain, and obtain timely, human - relevant data without
animal or human
testing.
In a study published in ACS» journal Molecular Pharmaceutics,
scientists report that they've developed a simple, «3D» laboratory method to
test asthma and allergy medications that mimics what happens in the body, which could help reduce the need for
animal testing.
A landmark new study, led by
scientists at Bowdoin and the California Academy of Sciences, explores the fascinating, little - known natural history of the face mite species Demodex folliculorum, using genetic
testing to link the microscopic
animal's evolution to our own ever - evolving human story.
He teamed up with Robert Seder of the Vaccine Research Center (VCR) at the National Institute of Allergy and Infectious Diseases in Bethesda, Maryland, and
scientists at other labs to
test immune responses to the vaccine in
animals.
Organovo chief
scientist Gabor Forgacs plans to
test the printed vessels in
animals late this year.
By disabling the gene for that key protein in
test animals, the
scientists were able to home in on the mechanism by which that brain region, known as the suprachiasmatic nucleus or SCN, becomes the body's master clock while the embryo is developing.
The lack of an
animal model has also prevented
scientists from
testing and fine - tuning experimental therapies for people.
The
scientists used a unique
testing facility, consisting of a trailer with computers set up next to a baboon enclosure, which the
animals could enter at will and perform trials on the touch - screen computers for as long as they pleased.
To
test the elephants» cooperation skills, a team of
scientists modified a classic experiment first administered to chimpanzees in the 1930s, which requires two
animals work together to earn a treat.
For example, nearly one in three say that
scientists in the United Kingdom can use
animals to
test cosmetics even though the practice has been banned for more than 15 years.
Due to lingering radiation from the 1986 meltdown of the Chernobyl nuclear power plant, humans aren't allowed to live there — but the region has become an accidental ecological
testing ground for
scientists interested in studying the effects of radiation on wild
animals.
Scientists will have to wait a while to find out whether cells that live longer in a
test tube will translate into longer lived
animals: Cows can live about 20 years.
On Monday, a U.K. court convicted four
animal - rights activists of threatening companies that supply an
animal testing laboratory, a verdict that U.K.
scientists see as a turning point in efforts to protect
animal researchers against illegal attacks.
The
scientists confirmed that these mice have learning problems by
testing them in a Morris water maze, a common lab
test of
animal learning and memory.
Scientists from the Florida campus of The Scripps Research Institute (TSRI) have successfully
tested a potent synthetic compound that prevents type 1 diabetes in
animal models of the disease.
section we deal with one of the biggest
animal rights myths — that all
animal testing is replaceable (but that
scientists opt for the more expensive route out of choice....?).
Heiko Woith and colleagues at the GFZ German Research Centre for Geosciences say
scientists must determine whether the link between the
animal behavior and the earthquake is based on clearly defined rules (such as the
animal's distance from earthquakes of a certain magnitude), whether the
animal behavior has ever been observed and not followed by an earthquake, whether there is a statistical
testing hypothesis in place to examine the evidence, and whether the
animal population is a healthy, among other questions.
How «Organs on a Chip» Will Revolutionize Medicine:
Scientists can now do research on live human organs without petri dishes or
animal testing.
Dec. 18, 2017 - Lawrence Livermore National Laboratory (LLNL)
scientists and engineers have developed a «brain - on - a-chip» device aimed at
testing and predicting the effects of biological and chemical agents, disease or pharmaceutical drugs on the brain over time without the need for human or
animal subjects.
Over the last few years,
scientists have been able to recreate accurate models of human organs by embedding living tissue onto chips, allowing them to study the effects of drugs and diseases without
testing on
animals or humans.
«
Scientists had identified and diagrammed these circuits in the late 80s and early 1990s, but there had been no way to
test their function in
animal models,» explained Dr. Kreitzer.
A trio of
scientists from different labs unveiled new data from
tests in cells and
animals.
Until now
scientists conducted most biomedical research through
animal testing — which often doesn't translate to humans — or in a petri dish, a static environment that doesn't let cells behave as if they are in the human body.»
Next steps for these
scientists include chemically optimizing the compound identified and
testing it in
animal models.
Scientists study how these new treatments work in
animals and may also
test new treatments on lab - grown
animal tissues or human tissues.
Once a
scientist identifies a drug that can be repurposed using the database, the drug's potential effect must be then
tested on a new disease, both in
animal models and human clinical trials.
In one
test, the
scientists injected dye into the
animals» blood.
The Salk
scientists now plan to make blood cells from the repaired stem cells and
test their effectiveness in
animals.
By using human derived structures,
scientists hope for better research and reduced
animal testing.
The
scientists tested their technique in
animal models and cardiomyocytes derived from human stem cells.
If a
scientist chooses to use a certain
animal in a lab environment, it makes a lot of sense to choose the same
animal when
testing similar or related research.
This binding is so complete that
scientists who wish to study the effects of low zinc concentrations in
test animals merely add soy bran to the
animals» diet.