In the
second Cell paper, researchers collaborated with scientists at the University of Cambridge, McGill University in Canada and several UK and European institutions to explore the role that epigenetics plays in the development and function of three major human immune cell types: CD14 + monocytes, CD16 + neutrophils and naïve CD4 + T cells, from the genomes of 197 individu
Cell paper, researchers collaborated with scientists at the University
of Cambridge, McGill University in Canada and several UK and European institutions to explore the role that epigenetics plays in the development and function
of three major human
immune cell types: CD14 + monocytes, CD16 + neutrophils and naïve CD4 + T cells, from the genomes of 197 individu
cell types: CD14 + monocytes, CD16 + neutrophils and naïve CD4 + T
cells, from the genomes
of 197 individuals.
In normal
immune responses, a
second type of helper
cells, known as TH2, secrete another batch
of cytokines, including one called interleukin - 4 (IL - 4) that turns off the cytokine release from TH1
cells.
In their latest work, reported online in the Journal
of Clinical Investigation, the scientists analyzed blood from such mice and identified two
types of autoimmune response directed specifically against the protein, with the first response directed by a specialized kind
of immune system
cells called T
cells and the
second by antibodies.