Sentences with phrase «secreted by bone»

FGF - 23 is secreted by bone - forming cells (osteoblasts / osteocytes) in response to increases in phosphorus intake.

Our laboratory has studied the role of various proprotein convertases in the degradation and cell biology of FGF - 23, a peptide hormone secreted by bone cells which controls phosphate metabolism via its action in the kidney.

Not exact matches

Yet in a study led by Aimy Sebastian, a graduate student in the School of Natural Sciences at UC Merced who is conducting her Ph.D thesis work under Loots, identified the secreted bone protein Sclerostin (SOST), as a key molecule dysregulated as a result of prostate cancer - bone microenvironment interactions.

The MSP was then taken from the environment by another protein called Ron, which causes the bone cells to secrete acids, destroying the bone.

Kandel showed — through a series of tests in mice — that it was almost certainly osteocalcin, which is secreted by cells in the bone, that regulated the gene's activity.

Synovial fluid: it is secreted by the synovial membrane and fills the joint cavity; it provides lubrication to the joint, reduces bone erosion and aids in joint mobility.

Osteocalcin, secreted by osteoblasts, is a non-collagenous protein hormone responsible for bone mineralization, ionized calcium homeostasis, insulin sensitivity, and testosterone biosynthesis.

The Opotowski team, which found that low vitamin A levels had as great an effect lowering BMD as did high vitamin A levels, suggested that vitamin A deficiency may contribute to increased fracture risk by allowing bone matrix to grow faster than it can be mineralized.12 Indeed, although the net effect of vitamin A is to stimulate osteoclasts and slow the growth of osteoblasts, vitamin A also causes osteoblasts to secrete a variety of enzymes and other proteins that are important to bone mineralization, including osteocalcin, which is a protein that plays a direct role in attracting and binding calcium within the bone matrix.6 By slowing the growth of the matrix but increasing the rate at which it is mineralized, adequate vitamin A helps to ensure sufficient bone densitby allowing bone matrix to grow faster than it can be mineralized.12 Indeed, although the net effect of vitamin A is to stimulate osteoclasts and slow the growth of osteoblasts, vitamin A also causes osteoblasts to secrete a variety of enzymes and other proteins that are important to bone mineralization, including osteocalcin, which is a protein that plays a direct role in attracting and binding calcium within the bone matrix.6 By slowing the growth of the matrix but increasing the rate at which it is mineralized, adequate vitamin A helps to ensure sufficient bone densitBy slowing the growth of the matrix but increasing the rate at which it is mineralized, adequate vitamin A helps to ensure sufficient bone density.

Testosterone helps signal the pituitary gland to produce growth hormone which then supplies the liver with the stimulus to secrete insulin growth factor 1 which works with GH to stimulate the production of new cells needed by the bones.