Sentences with phrase «secreted by the macrophages»
Biologic therapy removes the protein molecules being secreted by the macrophages.
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DHCA reduces interleukin 6 (IL - 6), a pro-inflammatory substance secreted by T cells and macrophages to stimulate immune response, by epigenetically modulating the non-coding sequence of the IL - 6 gene.
It is known that macrophages are an important component of the innate immunity against tumors and they are attracted by locally secreted chemokines [4].
The mechanism of action is based on the activation of macrophages to defend against tumors by direct tumor cytotoxicity and consequently they secrete cytokines which recruit secondary immune cells, presenting antigen to T cells [5 - 7].
In the tumor microenvironment, galectin 3 is produced and secreted by tumor cells, tumor - associated macrophages, and exhausted T cells.
The most potent activator of ILC3s is the cytokine IL - 23 [12], which is primarily secreted by activated macrophages and DCs.