Further expanding the array of functions attributed to Tregs, Rudensky found that when faced with tissue damage and inflammation,
they secrete a signaling molecule called amphiregulin, which mediates tissue repair and maintenance; the discovery established a central role for Tregs in inflammation and allergies.
Not exact matches
Bacterial cells communicate with one another by using chemical
signal molecules, which they synthesize and
secrete into their surroundings.
In lymph nodes, a particular type of stromal cells that forms a scaffold for lymphocytes to crawl around within the node normally
secretes an enzyme called autotaxin, which is responsible for the production of the lipid
signaling molecule, lysophosphatidic acid (LPA).
They cultivated human muscle cells and artificially synchronised them in the absence of a master clock, using a
signal molecule normally
secreted in the body.
IL - 6 is a cytokine, a
signal molecule that is produced and
secreted both by immune cells and by tumor cells and binds specifically to a receptor (IL - 6R) that is found on the surfaces of many cell types.
To assist with wound healing, mesenchymal stem cells from the gum tissue
secrete extracellular vesicles (labeled red) that contain the anti-inflammatory
signaling molecule IL - 1RA (labeled green).
We previously demonstrated that numerous Wnt
molecules are
secreted in the local milieu during regeneration and showed that MuSC self - renewal is in part controlled by non-canonical Wnt7a / PCP
signals sent by the regenerating myofibers.
Most well - characterized effector
molecules in other insects are
secreted into the hemolymph: in our study, 91.2 % of previously identified AMPs have bioinformatic evidence indicating presence of a
signal peptide.
Neuropeptides comprise a large class of
signaling molecules which are
secreted from neurons and transmit messages within the brain and across the nervous system.
Garrison is interested in a large class of
signaling molecules called neuropeptides which are
secreted from neurons and transmit messages within the brain and across the nervous system.
Although no
signaling molecules that act downstream of the Slif / TOR pathway have been identified yet, these fat body - derived
signals ultimately regulate the production of insulin - like peptides (Drosophila insulin - like peptides; Dilps)
secreted from the brain [10][9].
Plants
secrete a diverse set of peptides that play crucial roles as
signaling molecules to influence growth and development.
Briefly, full - length
secreted molecules and the entire ectodomains of membrane - embedded proteins were identified using transmembrane [28], GPI - anchor [29], and
signal peptide [30] prediction software.
The vasculature can influence neural stem cell proliferation and differentiation by providing a local source of
signaling molecules secreted from endothelial cells (1) as well as by delivering systemic regulatory factors (2).