Senescent cells
secrete inflammatory cytokines (TNF - alpha and IL - 6) that help drive pathological advancement of disease.
Not exact matches
The release of
inflammatory chemicals called «
cytokines» (proteins
secreted by specific cells involved in immunity and in inflammation) leads to biochemical reactions involving neurotransmitters.
Cells in the innate immune system respond immediately by
secreting inflammatory factors called
cytokines to stop the spread of infection.
They also
secreted higher amounts of
inflammatory cytokines.
Subsets of CD4 + T lymphocytes play pivotal roles both in initiating the
inflammatory process, by
secreting pro-
inflammatory cytokines, and by preventing inflammation, in part by
secreting regulatory
cytokines such as IL - 10 and TGFβ.
In addition, studies showed that the elimination of residual leukemia was primarily mediated by donor CD8 + cytotoxic T lymphocytes and NK cells, whereas the
inflammatory cytokines that are
secreted mainly by CD4 + Th cells have a very limited role in leukemia eradication but contribute significantly to the toxicity of GVHD (55).
A strong immune response whereby DCs are activated and can express antigens, as well as
secrete a number of
inflammatory cytokines that lead to the activation of other immune cells, such as NK cells.
Piperine also interferes with
inflammatory signaling mechanisms and inhibits pro-
inflammatory cytokines, which are small proteins
secreted by some cells and linked with a number of degenerative diseases.