Sentences with phrase «seeds of amyloid»

Yet such case studies can only ever provide circumstantial evidence that seeds of amyloid - β were transferred during the treatments.

«It is the best source of fresh human brain tissue available at the moment,» says Jucker, who plans to scrutinize it carefully under the microscope for anything that might resemble tiny clumps or seeds of amyloid - β.

Not exact matches

Collinge has access to some original samples of growth hormone stored by the UK Department of Health, and he is planning to analyse them for the presence of amyloid seeds and then inject them into mice.

Knowing the structures of pathological forms of amyloid seeds should help to design small molecules that bind to them and stop them doing damage, says biophysicist Ronald Melki at the Paris - Saclay Institute of Neuroscience, who works on α - synuclein strains.

A decade ago, these similarities prompted neuroscientist Mathias Jucker at the University of Tübingen in Germany to test whether injecting brain extracts containing misfolded amyloid - β into mice could seed an abnormal build - up of amyloid in the animals» brains.

Jucker, only half - jokingly, says he could imagine a future in which people would go into hospital every ten years or so and get the amyloid seeds cleared out of their brains with antibodies.

Researchers are also trying to work out what the putative amyloid seeds look like, and whether different «strains» of amyloids exist that are particularly damaging.

These results suggest that material containing aggregated IAPP seeds can induce the aggregation and deposition of new IAPP amyloid in cultured islets and that the formation of new amyloid deposits depends on the expression of endogenous hIAPP in the islets.

Dissociation of prion protein amyloid seeding from transmission of a spongiform encephalopathy

On that list is Vitamin E, a powerful antioxidant found in oils, nuts, seeds, whole grains and leafy green vegetables, which is associated with slower cognitive decline, a lower risk of dementia, and reduced accumulation of beta - amyloid proteins — a key culprit in Alzheimer's disease.

In the case of the eight patients in the study, Collinge said that it's likely they acquired a-beta amyloid seeds from the hormone harvested from the deceased elderly who donated their organs for that purpose.

Collinge admitted that more research needs to be done to fully understand how important a pathway the amyloid seeds might be in contributing to Alzheimer's, but that the latest results highlight «the growing paradigm shift in understanding that neurodegenerative disease [like Alzheimer's and Parkinson's] may be all about accumulation of [prion] seeds.»