Sentences with phrase «seen in normal mice»

DNA sequencing of sperm from the grandfather mice and their pups also revealed epigenetic marks on the gene encoding M71 that weren't seen in normal mice.

Not exact matches

These mice performed better than their normal counterparts on learning tests well into old age, and their brains did not exhibit the decline in neurogenesis typically seen in aged mice.

Normal mice saw benefits, too: Muscles and pancreas cells healed better in...

Normal mice saw benefits, too: Muscles and pancreas cells healed better in middle - aged mice that got rejuvenation treatments than in mice that did not.

Alzheimer's mice with normal BACE1 levels experienced a steady increase in plaques, clearly seen in samples of their brains.

Mice without the leptin gene, called ob / ob, overeat, weigh in at three to four times normal, and develop symptoms similar to the obesity - related diabetes seen in humans.

However, when the researchers knocked out SIRT1 in endothelial cells of 10 - month - old mice, then put them on a four - week treadmill running program, they found that the exercise did not produce the same gains seen in normal 10 - month - old mice on the same training plan.

The researchers then decided to see what would happen if they boosted sirtuin levels in normal mice as they aged.

To mimic those patient conditions, Schloss's former graduate student, Alyxandria Schubert tested 8 antibiotics in 16 different treatment conditions to see how they altered the normal gut microbiota of mice.

«It was particularly exciting to see plasticity in the neurons impaired by mHTT,» said Davidson, noting that in the HD mice, brain areas that had begun to atrophy recovered volume and permitted better motor function after the researchers restored mTORC1 activity to more normal levels.

As a final test to see whether parasites could directly access the brain from the blood, the researchers infected mice with a mixture of normal parasites and mutants that was unable to reproduce, each labeled in different colors.

«It was incredible to see that in adult mice, who have gone through normal development and aging, simply overexpressing Arc with a virus restored plasticity,» says co-first author Kyle Jenks, a graduate student in Shepherd's lab.

Next, Prins exposed the mice to elevated estrogen levels for two to four months, to mimic the normal rise in estrogen seen in aging men.

When the researchers turned off Lhx1 in the SCN of mouse embryos, the grown mice lacked distinctive biochemical signatures seen in the SCN of normal mice.

To see if the effect also works in reverse, the team asked whether mice grown in a germ - free environment would express genes encoding complement components differently than mice grown under normal conditions.

In mice with A-T, the cerebellum appears normal and they do not exhibit the obvious degeneration seen in the human braiIn mice with A-T, the cerebellum appears normal and they do not exhibit the obvious degeneration seen in the human braiin the human brain.

He notes, however, that other attempts to stimulate bone growth in mice by manipulating cell signaling proteins have produced denser than normal bones — and he's surprised that Helms's team didn't see the same.

To see what was happening in the brains of these ankyrin - G mutant mice, the researchers analyzed the cell components in inhibitory synapses connecting with pyramidal neurons, finding that two proteins known as GAT1 and GAD67 — responsible for making the neurochemical GABA that dials back nerve impulses — were at much lower levels in the synapses on pyramidal neurons in ankyrin - G mutant mice than in normal mice.

To see whether point mutations, which affect just one DNA base in mtDNA, are directly involved in aging, a team of researchers at the University of Washington in Seattle charted mtDNA mutation frequency in normal mice and «mitochondrial mutator» mice.

They found that the samples from the older normal mice had the most diversity of their gut microbes, including Clostridia and Bacteroides bacteria not seen in the younger mice that were still getting their nutrition entirely from mother's milk.

As seen through a microscope, the leg bone of a normal mouse (left) makes considerably less new bone than a mouse that produces high levels of a signaling protein, WNT7B, that stimulates new bone growth (shown in pink on the right).

Interestingly, this influence appears to work both ways — a mild reduction in disease symptoms was seen when HD mice were treated with normal glial cells.

To confirm that macrophages throw an entirely different molecular switch to turn on Nr4a1, the group exposed mice missing the monocyte E2 switch to a noxious toxin found in bacterial membranes, as a way of seeing whether macrophages can still mount normal inflammatory responses.

The enhanced endurance was seen in lab mice with a normal oxygen supply and those with oxygen restrictions which provided significant evidence that GW501516 targets and enhances skeletal muscle endurance and recovery time to a supraphysiological level.

this was the one thing with move that seemed to stand on its own... I don't mind the idea of HD wii sports either, as long as it really is 1:1... that was my only real complaint with the wii when it released... there was motion control, but it was gimmicky and registered «wiggles» into canned animations... not to mention the gamecube visuals... still not sold on Move though... for me to really want one, I want to see what they are doing with shooters... Socom 4 and killzone 3 could be very special for core gamers and motion controls if they are done right... if you can aim on screen in true 1:1 fashion while sitting comfortably at a «normal» gaming distance... it could rearrange how I play first person shooters on a console... developers are saying the Move has input latency of 21ms, which is roughly half of a DS3... and second only to a wired mouse / keyboard... need to see how it works though, as it is not always that simple... just saying that if it does what its supposed to... it could end up being the answer to shooters on a console... as much as I like playing shooters with 2 sticks... I can't argue that I miss the days of a mouse and keyboard (as well as PC being the only platform to get the best shooters on... no longer the case by any means)... but with a first person shooter, there is no wiggle room... pun intended... it has to register every mm of movement on screen... and do it quickly... not sure if it can yet...