Sentences with phrase «seen in the larger study»

«Strong statin - diabetes link seen in large study

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In 2019, those who rank in the 95th through 99th percentiles would see their after - tax incomes rise by more than 3 percent after receiving «the largest cuts as a share of income,» according to the studIn 2019, those who rank in the 95th through 99th percentiles would see their after - tax incomes rise by more than 3 percent after receiving «the largest cuts as a share of income,» according to the studin the 95th through 99th percentiles would see their after - tax incomes rise by more than 3 percent after receiving «the largest cuts as a share of income,» according to the study.
These risks and uncertainties include: Gilead's ability to achieve its anticipated full year 2018 financial results; Gilead's ability to sustain growth in revenues for its antiviral and other programs; the risk that private and public payers may be reluctant to provide, or continue to provide, coverage or reimbursement for new products, including Vosevi, Yescarta, Epclusa, Harvoni, Genvoya, Odefsey, Descovy, Biktarvy and Vemlidy ®; austerity measures in European countries that may increase the amount of discount required on Gilead's products; an increase in discounts, chargebacks and rebates due to ongoing contracts and future negotiations with commercial and government payers; a larger than anticipated shift in payer mix to more highly discounted payer segments and geographic regions and decreases in treatment duration; availability of funding for state AIDS Drug Assistance Programs (ADAPs); continued fluctuations in ADAP purchases driven by federal and state grant cycles which may not mirror patient demand and may cause fluctuations in Gilead's earnings; market share and price erosion caused by the introduction of generic versions of Viread and Truvada, an uncertain global macroeconomic environment; and potential amendments to the Affordable Care Act or other government action that could have the effect of lowering prices or reducing the number of insured patients; the possibility of unfavorable results from clinical trials involving investigational compounds; Gilead's ability to initiate clinical trials in its currently anticipated timeframes; the levels of inventory held by wholesalers and retailers which may cause fluctuations in Gilead's earnings; Kite's ability to develop and commercialize cell therapies utilizing the zinc finger nuclease technology platform and realize the benefits of the Sangamo partnership; Gilead's ability to submit new drug applications for new product candidates in the timelines currently anticipated; Gilead's ability to receive regulatory approvals in a timely manner or at all, for new and current products, including Biktarvy; Gilead's ability to successfully commercialize its products, including Biktarvy; the risk that physicians and patients may not see advantages of these products over other therapies and may therefore be reluctant to prescribe the products; Gilead's ability to successfully develop its hematology / oncology and inflammation / respiratory programs; safety and efficacy data from clinical studies may not warrant further development of Gilead's product candidates, including GS - 9620 and Yescarta in combination with Pfizer's utomilumab; Gilead's ability to pay dividends or complete its share repurchase program due to changes in its stock price, corporate or other market conditions; fluctuations in the foreign exchange rate of the U.S. dollar that may cause an unfavorable foreign currency exchange impact on Gilead's future revenues and pre-tax earnings; and other risks identified from time to time in Gilead's reports filed with the U.S. Securities and Exchange Commission (the SEC).
Also there is evidence of molecular mechanisms in the cell membranes that can amplify small changes in the field to produce large changes in neural activity.13 On the other hand, earlier tests of Kohler's theory found that interference with electrical gradients over the cortex had no effect on behavioral measures (see note 11 for reference to these studies).
For example, while we have not seen any large - scale research studies in this regard, we would predict that crimini mushrooms grown on composted materials that had previously been contaminated with residues of pesticides, heavy metals, or other unwanted substances would end up absorbing some of these contaminants into the brown button mushroom that we eat.
«It will be important to see whether these results can be confirmed in future, larger studies and in other populations,» said senior author Thomas Newman, MD, MPH, a professor of pediatrics and epidemiology and biostatistics at UCSF and a pediatrician at UCSF Benioff Children's Hospital.
To see if these patterns were valid in a wider population, they undertook the larger, county - wide study, conducting an analysis of births at Women and Children's, Millard Fillmore Suburban, Sisters of Charity Hospital and Mercy Hospital, located either in the city of Buffalo or its nearby suburbs.
The study saw New Yorkers using almost double the amount of the second largest weed - smoking city in the world: Karachi in Pakistan.
Recent years have seen a large rise in the number of humanists who are on SACREs, as documents such as the 2013 national framework, programmes of study and RE guidance have referred to teaching about non-religious beliefs such as Humanism.
As some biology textbooks and studies continue to sidestep the details of the amoeba and other microbes in favor of focusing on larger organisms, Spiegel sees a tragic irony: Amoebas and their ilk can best position budding researchers to explore the costs of sex, its evolution and alternatives to problems it may or may not solve.
Large swaths of the tropics and beyond may see crushing combinations of heat and humidity in coming decades, according to a new study.
The association recently gave Bowser funds for an expanded study, to see whether the biomarkers hold up in a larger population.
A study, published today in Science Advances, found that when scientists used noninvasive brain stimulation to disrupt a brain region called the temporoparietal junction (TPJ), people appeared less able to see things from the point of view of their future selves or of another person, and consequently were less likely to share money with others and more inclined to opt for immediate cash instead of waiting for a larger bounty at a later date.
More studies will need to be done to confirm whether the results of the smaller studies are seen in larger groups of patients.
The researchers have already begun a large study to see whether the test can pick up tumors in seemingly cancer - free women.
The scientists are now expanding their research to larger numbers of animals and they are also planning a study to look at addiction - like behaviours in obese people to see how well their results translate to humans.
«We were very curious to see what would happen if we were to change the expression pattern of Pax6 in developing mouse brain to mimic that observed in large - brained animals,» says Fong Kuan Wong, a PhD student in the lab of Wieland Huttner and first author of the study.
Kristoffer NT Månsson sees the study as a first step in a larger project.
To see if a president's speeches reflect egotism in American society at large, the team compared its results to studies of egotism in other cultural products, such as 20th - century books and songs.
The higher soybean yields seen in the study are sustained on these larger scales.
In the largest study of its kind to evaluate the relationship between vitamin D levels and coronary artery disease, vitamin D deficiency (20ng / mL) was observed in 70.4 percent of patients undergoing coronary angiography — an imaging test used to see how blood flows through the arteries in the hearIn the largest study of its kind to evaluate the relationship between vitamin D levels and coronary artery disease, vitamin D deficiency (20ng / mL) was observed in 70.4 percent of patients undergoing coronary angiography — an imaging test used to see how blood flows through the arteries in the hearin 70.4 percent of patients undergoing coronary angiography — an imaging test used to see how blood flows through the arteries in the hearin the heart.
The differences between children who attended Educare and children who did not attend were larger than differences seen in previous studies of similar programs, such as Early Head Start or home visiting programs.
For several years, geneticists in Oxford, led by Julian Hopkin of the Churchill Hospital, have been studying DNA from a large number of families to see how the allergic tendency, known as atopy, is passed down.
«I think this is a strong finding,» says Lone Simonsen, an epidemiologist at George Washington University in Washington, D.C. «It's good to see a carefully done, large study like this.»
Serious side effects with mefloquine seem to be rare, less than 1 % of users, and increases in formal diagnoses of depression and psychosis have not been seen in people returning from travel in any of the large database studies
Lloyd - Jones's editorial is based on a large new study published in the journal that looked at adults, ages 50 to 80, with cardiovascular disease who took extended - release niacin (vitamin B3) and laropiprant (a drug that reduces face flushing caused by high doses of niacin) to see if it reduced heart attack and stroke compared to a placebo over four years.
A new, 15 - year - long study, published online yesterday in PLoS Medicine, followed 6,441 men and women — both with and without the condition — in the National Heart, Lung and Blood Institute's large Sleep Heart Health Study to see if there was any correlation between apnea and a higher risk of dstudy, published online yesterday in PLoS Medicine, followed 6,441 men and women — both with and without the condition — in the National Heart, Lung and Blood Institute's large Sleep Heart Health Study to see if there was any correlation between apnea and a higher risk of dStudy to see if there was any correlation between apnea and a higher risk of death.
The advent of genomics and rapid sequencing techniques has seen HeLa cells used in numerous large - scale studies of gene function and expression.
In a pioneering study, Joshua Cowen and colleagues found that voucher schools in Milwaukee saw a large jump in math and reading scores the year after a new law required them to release the resultIn a pioneering study, Joshua Cowen and colleagues found that voucher schools in Milwaukee saw a large jump in math and reading scores the year after a new law required them to release the resultin Milwaukee saw a large jump in math and reading scores the year after a new law required them to release the resultin math and reading scores the year after a new law required them to release the results.
In the lab, they adapted the standard experimental technique for studying place cells: implanting electrodes directly into a rat's hippocampus and recording from them as the animal runs freely in a large box (see «A sense of place»In the lab, they adapted the standard experimental technique for studying place cells: implanting electrodes directly into a rat's hippocampus and recording from them as the animal runs freely in a large box (see «A sense of place»in a large box (see «A sense of place»).
Perhaps because students in the study got the targeted help they needed to catch up, Ludwig said, «These effects on schooling outcomes are larger — much larger — than what we see from so many other educational strategies.»
Type Ia supernovae are explosions that can be seen even in far - away galaxies and help astronomers study the large - scale structure of the Universe.
The US is now funding a large study of countries that used adjuvanted vaccines in 2009 to see if they may have caused narcolepsy.
The results are encouraging and we now need larger trials to understand whether the effects we saw in this study translate into long - term benefits, and to study how psilocybin compares to other current treatments.»
In the future, David Legg intends to further his research and study fossilised creatures from the Ordovician, the geological period that saw the largest increase in diversity of species on the planeIn the future, David Legg intends to further his research and study fossilised creatures from the Ordovician, the geological period that saw the largest increase in diversity of species on the planein diversity of species on the planet.
However, other studies find that the largest carbon balance variability is seen in wide - spread water - limited regions.
«When we compared the gene signature activity of glioblastoma cells from around 60 patients we found that a large number of patients could be divided into subgroups that showed a correlation between gene activity, tumor cell characteristics and cell of origin similar to the one we had seen in the mouse study.
Our study is the first of its kind in the world on airplane headache, and that is why we need more and larger studies that can repeat the experiment and see if our conclusions are accurate,» says Sebastian Bao Dinh Bui, AAU.
To see if mercury has comparable effects, Grandjean, along with Pál Weihe at the University of Southern Denmark, is conducting the largest study to date of children's cognition and behavior in a population routinely exposed to low levels of mercury.
For the original study published in Nature Physics, see «Large orbital polarization in a metallic square - planar nickelate.»
RTS, S is still widely seen as the most practical of these strategies, and it will be rolled out in 2018 in three sub-Saharan African countries, despite the fact that it protected just 27 % to 39 % of infants in large human studies.
Stronger Storms — Much of the country will experience severe thunderstorms, but major eastern and southeastern cities are likely to see the largest jumps in storm frequency, according to Purdue's Trapp — a finding buttressed by a NASA study earlier this year.
The strong reflection seen on Mercury is too large to be caused by a momentary «glint» off a crater wall, and when studied in more detail, shares the characteristics of reflections from the water ice seen on Mars and the icy moons of Jupiter.
In recent years we have seen extensive studies of different aspects of coherence and superposition, e.g. their possible (debated) role in biological systems, their experimental verification in double slit experiments with large molecules and also in their quantification in the framework of resource theorieIn recent years we have seen extensive studies of different aspects of coherence and superposition, e.g. their possible (debated) role in biological systems, their experimental verification in double slit experiments with large molecules and also in their quantification in the framework of resource theoriein biological systems, their experimental verification in double slit experiments with large molecules and also in their quantification in the framework of resource theoriein double slit experiments with large molecules and also in their quantification in the framework of resource theoriein their quantification in the framework of resource theoriein the framework of resource theories.
We included prospective cohorts with at least 50 cardiovascular disease events (mortality, morbidity, or both) to minimise the potential for reporting bias, in which large but unreliable effects might be seen in small studies.
A new NASA study provides space - based evidence that Earth's tropical regions were the cause of the largest annual increases in atmospheric carbon dioxide concentration seen in at least 2,000 years.
In the new study, the largest of its kind to date, the researchers randomly assigned 369 U.S. and Canadian men with prostate - related symptoms to take saw - palmetto capsules or an identical placebo.
The researchers presented their research as a working paper this weekend at the annual meeting of the American Sociological Association, and are now studying other states to see if their findings hold true in a larger sample size.
This has been seen in various studies, including one large research project called «the Million Woman» study and the nurses health study, which showed a connection to breast cancer and also an increased risk of heart disease and stroke in women using hormone replacement therapy.
«In our sample, I expected to see a large number of negative tweets based on traditional news coverage of the topic and because HPV can be portrayed as controversial because it brings together the fields of sexually transmitted infections, immunizations and cancer prevention,» said study co-author Philip Massey.
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