Sentences with phrase «segregation during mitosis»

Finally, as we and others have shown, errors in chromosome segregation during mitosis have dramatic secondary consequences on genome integrity, including translocations, deletions and chromosome shattering (chromothripsis).

We are particularly interested in the processes that ensure correct chromosome segregation during mitosis.

Heritable genetic variation is the result of genome instability during germ cell development, instability that arises through mutation, chromosome rearrangement or chromosome mis - segregation during mitosis or meiosis.

Not exact matches

When there is more (polyploidy) or less (haploidy), mitosis is more prone to errors during the segregation of the chromosomes and this activates p53.

It participates in the assembly of a bipolar spindle that ensures accurate segregation of chromosomes during mitosis.