Sentences with phrase «selection in the human genome»

Recent and ongoing selection in the human genome.

Targets of balancing selection in the human genome.

Positive selection in the human genome inferred from human — chimp — mouse orthologous gene alignments Clark, A. G., S. Glanowski, R. Nielsen, P. Thomas et al. 2003.

Positive selection in the human genome inferred from human — chimp — mouse orthologous gene alignments.

An international team of scientists from Australia, the Netherlands, Estonia and the United States has detected significant signatures of natural selection in the human genome that influence traits associated with fertility and heart function.

In one of the first comprehensive genome scans for selection, to be published online March 7, 2006, in the Public Library of Science - Biology in a paper, titled «A Map of Recent Positive Selection in the Human Genome,» the researchers found widespread evidence of evolution in all of the populations studied.

Not exact matches

Comparisons of the Neandertal genome to the genomes of five present - day humans from different parts of the world identify a number of genomic regions that may have been affected by positive selection in ancestral modern humans, including genes involved in metabolism and in cognitive and skeletal development.

«New algorithm can pinpoint mutations favored by natural selection in large sections of the human genome.»

A team of scientists has developed an algorithm that can accurately pinpoint, in large regions of the human genome, mutations favored by natural selection.

Once transferred into the human genome, however, these alleles became subject to natural selection, which was more effective in the larger human populations and has removed these gene variants over time.

Neanderthal genetic material is found in only small amounts in the genomes of modern humans because, after interbreeding, natural selection removed large numbers of weakly deleterious Neanderthal gene variants, according to a study by Ivan Juric and colleagues at the University of California, Davis, published November 8th, 2016 in PLOS Genetics.

In the current study, Chaput designed an in vitro selection strategy to identify human genome sequences that initiate cap - independent translatioIn the current study, Chaput designed an in vitro selection strategy to identify human genome sequences that initiate cap - independent translatioin vitro selection strategy to identify human genome sequences that initiate cap - independent translation.

In particular, the Neandertal genome sequence can now be used to catalog changes that have become «fixed» (are invariant within a population or species) in modern humans during the last few hundred thousand years and should be helpful for identifying genes affected by positive selection since humans diverged from NeandertalIn particular, the Neandertal genome sequence can now be used to catalog changes that have become «fixed» (are invariant within a population or species) in modern humans during the last few hundred thousand years and should be helpful for identifying genes affected by positive selection since humans diverged from Neandertalin modern humans during the last few hundred thousand years and should be helpful for identifying genes affected by positive selection since humans diverged from Neandertals.

Sabeti adds, «The study of natural selection in humans is incredibly active right now, and this paper is part of a wide array of exciting new genome - wide surveys.»

As they report in this month's issue of Genome Research, the results were not consistent with balancing selection over the last half million years of human evolution but more likely due to as yet unknown selective pressures.

In the study, the researchers applied genomic methods to identify candidate regions in the human genome showing positive selection regions with musical aptitudIn the study, the researchers applied genomic methods to identify candidate regions in the human genome showing positive selection regions with musical aptitudin the human genome showing positive selection regions with musical aptitude.

In Eric Lander's lab at the Broad Institute, she scanned the entire human genome to figure out which genes have changed within the last 10,000 years and which have spread rapidly in the human gene pool due to natural selectioIn Eric Lander's lab at the Broad Institute, she scanned the entire human genome to figure out which genes have changed within the last 10,000 years and which have spread rapidly in the human gene pool due to natural selectioin the human gene pool due to natural selection.

Natural selection on protein - coding genes in the human genome.

Simultaneous inference of selection and population growth from patterns of variation in the human genome.

The paper itself is very statistical in nature, with various «selection models» applied to determine the demographic and selective effects on amino acid variation in the human genome.

Natural selection and the distribution of identity - by - descent in the human genome Albrechtsen, A., I. Moltke, and R. Nielsen.

Natural selection on protein - coding genes in the human genome Bustamante, C. D., A. Fledel - Alon, S. Williamson, R. Nielsen et al. 2005.

Selection - free genome editing of the sickle mutation in human adult hematopoietic stem / progenitor cells.

By scanning the entire human genome in search of genetic variations that may signal recent evolution, University of Chicago researchers found more than 700 genetic variants that may be targets of recent natural positive selection during the past 10,000 years of human evolution.

In this study, two researchers from the University of Pennsylvania, Kelsey E. Johnson and Benjamin F. Voight, wanted to investigate how shared positive selection pressures over different populations were affecting the human genome.