Sentences with phrase «selective agonist»
for article Development of a selective agonist for relaxin family peptide receptor 3.
http://www.nature.com/
As an intern at Smith Kline and French in Philadelphia, Pennsylvania, Bowen was a medicinal chemist, charged with finding a more selective agonist — an active binding agent — to be used in a spray to treat asthmatics.
«It thus appears quite possible that these selective agonists will be administered in the future to patients who are candidates for allogeneic stem cell transplants.
Not exact matches
The researchers showed that a two - day treatment regimen with partial or selective PPAR - γ agonists (Telmisartan and Rosiglitazone — both FDA - approved drugs) ameliorated the pathological outcomes of infection in mice by inducing expression of glucose transporters.
The newly developed CB1 receptor selective antagonist SR141716A was found to reverse cannabinoid agonist (WIN55212 - 2 or CP55940)- induced adenylyl cyclase inhibition.
Liu, J., Yu, L. F., Eaton, J. B., Caldarone, B., Cavino, K., Ruiz, C., Terry, M., Fedolak, A., Wang, D., Ghavami, A., Lowe, D. A., Brunner, D., Lukas, R. J., Kozikowski, A. P. Discovery of Isoxazole Analogs of Sazetidine - A as Selective alpha4 beta2 - Nicotinic Acetylcholine Receptor (nAChR) Partial Agonists for the Treatment of Depression, Journal of medicinal chemistry 2011 54, 7280 - 7288
A Biomarker - Directed Phase 2 Trial of SY - 1425, a Selective Retinoic Acid Receptor Alpha Agonist, in Adult Patients with Acute Myeloid Leukemia (AML) or Myelodysplastic Syndrome (MDS)
Determination of the dose of agomelatine, a melatoninergic agonist and selective 5 - HT (2C) antagonist, in the treatment of major depressive disorder: a placebo - controlled dose range study.
Selective 5 - hydroxytryptamine 2C receptor agonists derived from the lead compound tranylcypromine: Identification of drugs in several animal models of CNS related disorders.
SILEO is an oromucosal gel formulation of dexmedetomidine, a highly selective alpha - 2 adrenoceptor agonist that blocks norepinephrine.
SILEO is an oromucosal gel formulation of dexmedetomidine, a highly selective alpha - 2 adrenoceptor agonist that blocks norepinephrine release, a chemical in the brain that is involved with the development of fear and anxiety.