Selective plane illumination (SPIM) uses a thin sheet of light to illuminate only the plane of interest, reducing phototoxicity by drastically cutting total light dose and allowing for prolonged specimen imaging.
Marianas LightSheet ™ merges the low phototoxicity and large specimen handling of dual inverted
selective plane illumination (diSPIM) with the power and flexibility of a live - cell microscope system.
The second microscope, described in a paper published in Nature Biotechnology online on October 13, builds on
selective plane illumination microscopy (SPIM).
The technique, called microenvironmental
selective plane illumination microscopy (meSPIM), uses exceptionally long, thin beams of laser light to trigger fluorescence in a sample, causing it to glow.
Not exact matches
After this initial application, Stelzer's group described the single -
plane or
selective -
plane illumination microscope (SPIM).