Sentences with phrase «sensed by leptin»
Leptin circulates in the blood and crosses into the brain, where it is sensed by leptin receptors expressed on neurons in the hypothalamus.
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The decrease in leptin levels is accompanied by several other negative effects which everyone wanting to lose fat would like to avoid, such as overall metabolic slow - down (often called metabolic adaptation), a decrease in energy and strength levels, increase in appetite, reduced sense of well - being and decreased motivation.
Whether one burns glucose or fatty acids, or ketones from fatty acids, will be determined by powerful nutrient sensing hormones particularly insulin and leptin, and to be healthy these must be able to have their messages heard.