Sentences with phrase «sensitive ion channel»
Structure of heat - sensitive ion channel TRPV1, the receptor for capsaicin, the active ingredient in hot chile pepper.
https://www.bcm.edu/
The movements and behaviour of fruit flies, genetically engineered to carry a heat - sensitive ion channel, can be controlled with a precisely aimed infrared laser.
Rinsing with menthol - flavored mouthwash causes a tingly, cooling sensation because the compound triggers a cold - sensitive ion channel in sensory neurons.
«We found that these neural crest cells contain temperature - sensitive ion channels that typically are found in your sensory neurons,» Benner said.
They also inserted the light - sensitive ion channels into a different set of neurons in the medulla: glutamatergic neurons, which release the neurotransmitter glutamate.
In the new study, scientists focused on temperature - sensitive ion channels that open when they become hot enough.
Whereas in the nematode experiment the researchers targeted nanoparticles to temperature - sensitive ion channels that naturally exist in the membranes of the worms» nerve cells, the scientists inserted the gene for a heat - activated ion channel called TRPV1 into the human and rat cells.
«The really interesting thing they did was to genetically engineer cells to express heat - sensitive ion channels — that's a real innovation, in the first part of the paper.»
In the case of the modified fruit fly, when infrared light impinges on a specific region, the temperature at this point is raised to 30 Celsius from ambient temperature, which alters the engineered thermo - sensitive ion channels and so infrared light.
In the system, nanoparticles injected into the brain convert a gentle, external magnetic field into heat, which triggers heat - sensitive ion channels that have been genetically engineered into neurons.
The basis of this technique is to genetically modify neurons to express light - sensitive ion channels such as excitatory channelrhodopsin or inhibitory halorhodospin and then use light to control the on / off status of neuronal excitation.
Not exact matches
Hair - cell physiologists don't know yet what the pore — called an ion channel — looks like, but some interesting biophysical properties suggest the channel is very fast and sensitive.
In us and other mammals, that message increases the activity of a molecular pore, called the TRPV1 ion channel, causing the cell to become more sensitive to touch or heat.
«We demonstrated some time ago that a molecule called AAQ is capable of causing nerve cells to become light - sensitive, because it modifies the behavior of ion channels in their surface membranes,» Trauner says.
We found that RGCs are the sole retinal neuron that express TRPV4, a pressure - sensitive channels that is permeable to calcium ions.
They also showed that these ion channels became more sensitive to GABA in type 2 diabetes and that GABA helps regulate insulin secretion.