Sentences with phrase «sensitive tumor models»

In the sensitive tumor models, the ability of anti — cytotoxic T lymphocyte — associated protein 4 or anti — programmed cell death 1 therapy to increase vessel perfusion strongly correlated with its antitumor efficacy.

Not exact matches

«We hope that our mouse model, which allows us to combine drug testing and genetic analysis, will provide a deeper understanding of why tumors are sensitive or resistant to drugs,» states Ian Frew.

Here, we show that ICB increased tumor vessel perfusion in treatment - sensitive EO771 and MMTV - PyVT breast tumor as well as CT26 and MCA38 colon tumor models, but not in treatment - resistant MCaP0008 and 4T1 breast tumor models.

Injecting breast cancer with oxygen - filled microbubbles makes tumors three - times more sensitive to radiation therapy and improves survival in animal models of the disease.