Sentences with phrase «sensitivity alleles»

Taken together, these studies support the notion that collectivism can protect against psychopathology in populations with a high proportion of social sensitivity alleles.

Conversely, for those with these social sensitivity alleles the experience of social loss can precipitate psychopathology.

Rather, it would suggest that collectivism was «stickier», representing a better fit in populations with a high proportion of putative social sensitivity alleles (Lieberman, 2009).

This social construction of the self may function akin to an implicit social support network (Kim et al., 2008) that is likely to buffer individuals with social sensitivity alleles from the adverse consequences of stress and improve life satisfaction.

This increase in psychopathology following relocating to an individualistic culture among members of ethnic groups with a high proportion of social sensitivity alleles extends to other phenotypes such as social anxiety (Okazaki, 1997) and subclinical depression (Tafarodi and Smith, 2001).

This suggests that the reduced lifetime prevalence of depression in populations with a high prevalence of social sensitivity alleles may be due to the increased levels of collectivism in those populations.

Given that there is a higher prevalence of these putative social sensitivity alleles in East Asian populations than in Caucasian populations, there may be a relationship between the relative proportion of these alleles and the predominant cultural forms in a population.

Similarly, individualism may have represented a better fit for populations with a low proportion of social sensitivity alleles where less reactivity to social rejection or exclusion would have been beneficial.

In line with the social sensitivity hypothesis, a potential explanation for this relationship is that collectivism improves emotional well - being in populations with a high prevalence of social sensitivity alleles.

The relationship between allele frequency and depression was partially mediated by individualism — collectivism, suggesting that reduced levels of depression in populations with a high proportion of social sensitivity alleles is due to greater collectivism.

Conversely, does greater acculturation of Caucasian immigrants to East Asian cultures confer greater protection against psychopathology in individuals with social sensitivity alleles?

Here, we review recent work that has demonstrated a robust cross-national correlation between the relative frequency of variants in these genes and the relative degree of individualism — collectivism in each population, suggesting that collectivism may have developed and persisted in populations with a high proportion of putative social sensitivity alleles because it was more compatible with such groups.

Thus, collectivism may be more compatible with populations possessing a high proportion of social sensitivity alleles and may lead to higher levels of well - being in such populations.

A robust relationship was found such that the 5 - HTTLPR short allele, which we have referred to here as a social sensitivity allele, was much more prevalent in collectivistic populations than individualistic populations.

Again, the putative social sensitivity allele, the G allele, was more prevalent in populations with greater collectivism.

Not exact matches

In addition, the clinical sensitivity of tests for common risk alleles is not necessarily high.

It should be noted that the sensitivity for calling SNPs represents an upper bound for calling somatic mutations, since the latter often display mutant allele fractions less than 50 %.

Campbell, M.C.; Ranciaro, A.; Froment, A.; Hirbo, J.; Omar, S.; Bodo, J.M.; Nyambo, T.; Lema, G.; Zinshteyn, D.; Drayna, D.; Breslin, P.A.; Tishkoff, S.A. (2012) Evolution of functionally diverse alleles associated with PTC bitter taste sensitivity in Africa.

There is evidence that minor alleles of both DRD2 and DRD4 (A1 and 7R respectively) decrease the sensitivity and / or concentrations of their respective receptors [17 — 24].

Frequency of the mutant MDR1 allele associated with ivermectin sensitivity in a sample population of collies from the northwestern United States.

In particular, it was the G allele that was associated with greater sensitivity to rejection.

Thus, in all three cases (5 - HTTLPR, A118G, MAOA - uVNTR), the alleles hypothesized to influence social sensitivity were more prevalent in collectivistic cultures.

Previous studies have indicated that the 7 - repeat allele is under positive selective pressure, and our results are consistent with the hypothesis that the DRD4 7 - repeat allele increased children's sensitivity to environmental factors such as parenting.