Sentences with phrase «sensory hair cells»

When the head rotates, inertial drag of endolymph within the duct acts upon sensory hair cells that modulate the firing rates of primary vestibular afferent neurons.

The researchers removed the organ of Corti, which is housed within a seashell - shaped cavity called the cochlea and contains sensory hair cells, from newborn mice and kept the cells alive in culture plates.

Human inner ear organoid with sensory hair cells (cyan) and sensory neurons (yellow).

Implantable prostheses designed to deliver electrical stimuli directly to the auditory nerve hold considerable promise for people with a type of deafness in which the sensory hair cells of the inner ear are damaged

Based on previous studies, researchers have hypothesized that recreational noise exposure might damage the circuitry between sensory hair cells in the inner ear and their auditory nerve targets that deliver information to the brain.

When the head accelerates or decelerates, they bend the sensory hair cells and send a signal to the brain telling it which way is up.

In the inner ear of vertebrates, the balance system consists of three semicircular canals that contain fluid and sensory hair cells that detect movement of the head.

«When sensory hair cells in the ear die, they are not repopulated.

In the recessive deafness model, gene therapy with TMC1 restored the ability of sensory hair cells to respond to sound — producing a measurable electrical current — and also restored activity in the auditory portion of the brainstem.

Sensory hair cells in the cochlea of a Beethoven mouse treated with TMC2 gene therapy.

CIB2, which is short for calcium and integrin - binding protein 2, is essential for the structure of stereocilia, the structures at the top of the sensory hair cells in the inner ear.

As a result, the sensory hair cell bundles that receive sound and signal the brain deteriorate and become disorganized, leading to profound hearing loss.

Not exact matches

Specialized sensory neurons in the inner ear, called hair cells, are responsible for the detection of sounds, and this information is transmitted to the auditory cortex via several intermediate structures.

The inner ear comprises the hearing organ or cochlea, together with the five balance organs (the saccule, utricle and three semicircular canals), which contain the sensory cells, or hair cells, that detect mechanical vibrations and convert them into electrical signals.

Studies of deafness often emphasize the role of hair cells, the sensory cells that transmit sound signals to the brain.

In the early 2000s, cell biologists linked cyst formation to gene mutations that affect the primary cilia, hair - like projections from cells that seem to act as sensory antennae.

Researchers from the Eaton - Peabody Laboratories of the Massachusetts Eye and Ear and Harvard Medical School have created a new mouse model in which by expressing a gene in the inner ear hair cells — the sensory cells that detect sound and sense balance — protects the mice from age - related hearing loss (ARHL) and noise - induced hearing loss (NIHL), the two most common forms of deafness.

To deliver the healthy gene, the team inserted it into an engineered virus called adeno - associated virus 1, or AAV1, together with a promoter — a genetic sequence that turns the gene on only in certain sensory cells of the inner ear known as hair cells.

«In mammals, hair cells are the sensory cells of the ear,» McDermott said.

Hearing aids are mostly used in people who suffer from hearing loss because of damage to hair cells, the small sensory cells in the inner ear.

A research advance co-led by Case Western Reserve University School of Medicine's Kumar Alagramam, PhD, may stop the progression of hearing loss and lead to significant preservation of hearing in people with Usher syndrome type III, a form of hereditary hearing loss linked to defects in the sensory «hair» cells in the inner ear.

Researchers knew that cells in the inner ear below hair cells — known as supporting cells — can become the sensory cells themselves when stimulated by a protein that blocks Notch signaling, which is an important mechanism for cell communication.

We detect sound using sensory cells sporting microscopic hairlike projections, and when these so - called hair cells deep inside the inner ear are destroyed by illness or loud noise, they are gone forever.

Implants can work in place of the hair cells, but if the sensory neurons are damaged, hearing is still limited.

We report here that inner ears of Lcc / Lcc mice fail to establish a prosensory domain and neither hair cells nor supporting cells differentiate, resulting in a severe inner ear malformation, whereas the sensory epithelium of Ysb / Ysb mice shows abnormal development with disorganized and fewer hair cells.

Ordinarily, Coffin specializes in fish hearing — studying the hair - like tufts of sensory cells arrayed along each side of zebrafish in what is called the lateral line.