Sentences with phrase «sequence analysis showed»

The sequence analysis showed that no off - target mutation occurred.

Despite these differences, DNA sequence analysis shows that the core motors are ancestrally related.

JOURNAL: B. vonHoldt et al. «Whole - genome sequence analysis shows that two endemic species of North American wolf are admixtures of the coyote and gray wolf.»

** 16S rRNA Next Generation Sequencing Analysis Shows Bacteria in Alzheimer's Post-Mortem Brain — David C. Emery — Frontiers in Aging Neuroscience

Not exact matches

The drill hole intersected a thick repetitive sequence of mafic and felsic sediments which showed no major structural deformation, a potential host for gold mineralisation, with geochemical analysis revealing alteration and mineralisation based on micro analysis of the cores by world class scientists from CODES in Tasmania.

An expanded analysis of colorectal cancer sequences in The Cancer Genome Atlas database showed a high incidence of YME1L1 mutations.

Using a combination of old - fashioned clinical observation and modern biochemical analysis, he has shown that a person's appetite and their eating behavior can be linked to specific genes — and that even a tiny defect such as the absence of a single nucleic acid in a sequence of DNA can lead to runaway weight gain.

Interestingly, our analysis showed that Ariche's mitochondrial genetic make - up most closely matches that of the sequence of a particular modern day individual from Portugal,» Professor Matisoo - Smith says.

By comparing the two sequences with more recent ones, Gemmel was able to show that HIV - 1 first entered humans about 1908, not 1931, as earlier analyses with just the 1959 sample found.

The few studies that have included analysis of ribosomal DNA thus far have shown that the number of copies of the repetitive sequences expand and contract all the time.

«Our cell biological analysis show that a helicase, called Pfh1, binds to specific guanine - rich DNA sequences in the yeast cell.

Deep sequencing analysis has shown that this is highly unlikely in the case of J3 as no sequences were generated by deep sequencing of the seven naïve llamas or three other immunized llamas that share greater identity with J3 than its putative germ line V gene.

Consistent with the hypothesis that rice centromere 8 is a relatively new centromere, the amount of CentO it contains is small and sequence analysis of the LTRs of the CRR - class retroelements shows that they have recently inserted into the region.

In contrast, the deep sequencing analysis of VHH present at t = 54 shows no over-representation of the sequences which share higher levels of identity with the neutralizing VHH than the germ line (Fig. 6).

Using this «Ribotag» approach tissue - specific changes under DR have been measured in muscle, fat, gut, heart, neurons, germline and malpighian tubules, showing a highly tissue specific response upon DR.. We are developing mechanistic models of gene expression regulation and conducting comprehensive bioinformatics analyses on UTRs, promoters and the coding sequences of various elements of differentially regulated genes.

Bootscanning analysis was initially performed with all 95 unique, fully - sequenced adenovirus genomes in GenBank (data not shown).

On the other hand, our post hoc analysis shows that the sequencing test result may alter clinical decisions even in women at low risk for trisomy 21.

The difficulty in measuring such a small increment in chromosome 21 DNA concentration has recently been overcome with the use of massively parallel genomic sequencing.20 This technique can identify and quantify millions of DNA fragments in biological samples in a span of days.23 Three cohort studies have shown the feasibility of using the technique to identify fetuses with trisomy 21 by analysis of maternal plasma DNA.24 25 26 The sample numbers studied were small because, typically, only a few samples could be analysed in each sequencing run.

Here we show that CRISPR / Cas9 systems can have off - target cleavage when DNA sequences have an extra base or a missing base at various locations compared with the corresponding RNA guide strandâ $ ¦ Our results suggest the need to perform comprehensive off - target analysis by considering cleavage due to DNA and sgRNA bulges in addition to base mismatches.

Our phylogenetic analysis of newly sequenced viruses shows that subsets of genomes cluster primarily by geographic location, and secondarily by time of virus isolation.

The new phylogenetic analyses use the same model as the original paper but when additional modern Aboriginal and African sequences are added they show that all the ancient Australian sequences are well within what is expected for modern human variation.

By performing a meta - analysis of rare coding variants in whole - exome sequences from 4,133 schizophrenia cases and 9,274 controls, de novo mutations in 1,077 family trios, and copy number variants from 6,882 cases and 11,255 controls, we show that individuals with schizophrenia carry a significant burden of rare, damaging variants in 3,488 genes previously identified as having a near - complete depletion of loss - of - function variants.

«Our analysis of null embryos shows how single - cell RNA sequencing can provide a widely applicable approach for re-evaluating the function of key regulators», said John Marioni.

The most recent analyses of the TCGA sequencing project from ∼ 962 patients» tumors show only a couple of mutations in β - catenin or GSK3B (which degrades it).

BIOHM's Gut Report will show consumers exactly which microorganisms are in their gut through our DNA deep sequencing analysis of your microbiome (your body's native eco-system made of microorganisms).

Sequence analysis of the 283 bp crd3 - affected amplicon from primer pair 7 showed that exons 15 and 16 are absent from affected cDNA.

These findings are in keeping with evidence from a meta - analysis by Durlak et al. [3], which showed larger effect sizes (0.69 versus 0.01) for school - based social - emotional interventions (N = 213 interventions involving 270 034 children aged 5 — 13 years) that followed principles including, structure, sequenced learning, active involvement and repetition.