Sentences with phrase «sequence data from»

Recent updates in sequencing technology have made it possible to obtain Gigabases of sequence data from one single flowcell.

A collection of genome, gene, and transcript sequence data from several sources, including GenBank, RefSeq.

By analyzing genome sequence data from human populations, including 1269 individuals from sub-Saharan Africa, we identify a diverse array of large copy number variants affecting the host invasion receptor genes GYPA and GYPB We find that a nearby association with severe malaria is explained by a complex structural rearrangement involving the loss of GYPB and gain of two GYPB - A hybrid genes, which encode a serologically distinct blood group antigen known as Dantu.

A genome - wide FST scan comparison with previous sequence data from an area in West Africa with higher infection endemicity indicates that regional gene flow prevents genetic isolation, but revealed allele frequency differentiation at three drug resistance loci and an erythrocyte invasion ligand gene.

Performance is compared to sequence data from single technology platforms.

SciLifeLab researchers present genome - wide sequence data from ancient and present - day humans from Greenland, Arctic Canada, Alaska, Aleutian Islands, and Siberia.

He currently coordinates the Exome Aggregation Consortium (ExAC), which has aggregated and jointly processed exome sequence data from over 60,000 individuals, made publicly available through the widely - used ExAC browser (exac.broadinstitute.org).

The deCODE team was able to develop such a large dataset and catalogue of these mutations correlating whole - genome sequence data from thousands of individuals and multiple generations of families with information on the age of parents at the time their children were born.

Sequence data from the SMRT cells were assembled with HGAP17 (version 2.3.0), assuming an assembly size of 30 Mb.

In these studies, sequence data from several thousands of individuals is compared to find disease - associated genes where cases have a higher load of genetic variants that are likely to disturb gene function, compared to the controls.

If you use sequence data from any of the other Pseudomonas genome sequences, please acknowledge the appropriate genome project and genome sequence publication

has published a paper in PNAS on June 16 (see abstract and link below) in which they use genome sequence data from several preserved passenger pigeons to infer long - term demographic trends in the bird.

First, the researchers analyze sequence data from an individual's tumor and identify four to 10 genes altered in the cells.

In addition, we analysed sequence data from sixty individuals representing six closely related species from Lake Victoria, and show genome - wide diversifying selection on coding and regulatory variants, some of which were recruited from ancient polymorphisms.

The large volume of sequence data from novel organisms generated by metagenomic projects has triggered the development of specialized databases and tools focused on particular groups of organisms or data types.

The complete genome sequence data from the collected viruses will not only expand our knowledge of the virulence factors, but provide detailed information on evolution and transmission of RSV strains, host - pathogen interactions, and pathogen - microbiome relationships that occur during viral infection.

Analysis was performed on sequence data from 16,434 previously identified 1 kb - long loci26.

To construct a genome sequence data set, in addition to the three ancient samples, we examined whole - genome sequence data from 96 modern canids.

The researchers drew on H. pylori sequence data from 370 people in 27 populations, some from previous samples, others they collected themselves from Africans and American Indians.

In addition, NIH - funded researchers who generate full genome sequence data from HeLa cells will be expected to deposit their data into a single database for future sharing through this process.

Researchers investigated the glycophorin area of the genome in more detail than before using new whole - genome sequence data from 765 volunteers in the Gambia, Burkina Faso, Cameroon and Tanzania.

Under the policy, biomedical researchers who agree to abide by terms set forth in the HeLa Genome Data Use Agreement will be able to apply to NIH for access to the full genome sequence data from HeLa cells.

The new controlled access policy for full genome sequence data from HeLa cells will give the Lacks family the ability to have a role in work being done with the HeLa genome sequences and track any resulting discoveries.

The plan is to scale up to collecting whole - tumor genome sequence data from 3,000 to 4,000 patients annually.

The SC3 tool was then used to analyse single - cell RNA - sequence data from two patients diagnosed with myeloproliferative neoplasm (MPN) blood cancers.

They have since collected chloroplast sequence data from six different plant species that spread their seeds in a variety of ways, and will use CallHap to investigate how their seed dispersal methods might perform in response to climate change.

In contrast, analysis of sequence data from early in the outbreak indicated rapid mutation.

By comparing proteomic and RNA - sequencing data from people on different exercise programs, the researchers found evidence that exercise encourages the cell to make more RNA copies of genes coding for mitochondrial proteins and proteins responsible for muscle growth.

Prompted by this initial finding, the team searched for similar structural alterations in sequencing data from a total of 10,210 samples deposited in the Cancer Genome Atlas.

By comparing the sequencing data from these three sources, they were able to identify microRNAs from dodder that had entered the plant tissue.

In a test designed to show how the tool would be used in actual practice, Dr. Wang retrospectively tested iCAGES using detailed sequencing data from a patient with lung cancer.

To study gene expression, they then examined RNA sequencing data from 25 of the biliary - phenotype cancers and 44 hepatocellular cancers.

To answer that question, they analyzed genome sequencing data from The Cancer Genome Atlas and epidemiologic data from the Cancer Research UK database, developing a mathematical model that allowed them to determine the proportion of cancer mutations that resulted from R, hereditary or environmental mutations, respectively.

The study compared whole - exome sequencing data from 19 patient samples of mucosal melanoma to 135 samples of sun - exposed melanoma.

The Johns Hopkins team tested ImmunoMap's ability to correlate immune responses on receptor sequencing data from T - cells in the tumors of 34 patients with cancer enrolled in a nationwide clinical trial of the immunotherapy drug nivolumab.

Given the importance of this strain as a major cause of food poisoning, Palsson's Systems Biology Research Group recently sequenced its genome using a combination of sequencing data from instruments made by Pacific Biosciences and Illumina.

His collaborators, a team of experts in the genetics of skin disease, found interesting and unexpected variations in whole exome sequencing data from patients with eczema.

To search for these, the authors combined sequencing data from 22 cats, including both domestic and wildcat breeds.

Ultimately, I landed a job in the Medical Genomics Group, charged with the analysis of sequencing data from our high - throughput pipelines.

They used a method to identify genes that are co-expressed with already known endothelial - enriched genes and analysed RNA sequencing data from 124 unprocessed tissue samples from 32 different organs.

In a paper published in Nature in September 2013, we describe results of the largest study to date integrating RNA and genome sequencing data from multiple human populations, and provide a comprehensive map of how genetic variation affects the transcriptome.

We used mRNA sequencing data from the GTEx project (V6, Supplementary Table 1 and 2), and the derived gene and transcript quantifications obtained on Gencode26 V19.

To help tease out cancer's inherited components, the new study adds analysis of the sequencing data from the patients» normal cells that contain the «germline» information.

All sequencing data from the PCR products were assembled using Vector NTI (Invitrogen), compiled and edited by using Bioedit (Version 7.0.5.3).

Past genomic studies of cancer compared sequencing data from patients» healthy tissue and the same patients» tumors.

The authors combined exome sequencing data from 10,437 individuals representing five ancestry groups (European, South Asian, East Asian, Hispanic, and African American) with equivalent data from the WGS study for a joint dataset comprising 12,940 individuals.

Further, we intend to use whole genome sequencing data from Leonardo's remains to better understand his extraordinary talents and visual acuity through genetic associations.

A combination of sequencing data from two different platforms, as suggested by Nothnagel et al. [5] for the reduction of false positives in newly identified SNVs, is only of limited use for combining the strengths in coverage of different genomic regions.

npReader (jsa.np.f5reader) is a program that extracts Oxford Nanopore sequencing data from FAST5 files, performs an initial analysis of the date and streams them to real - time analysis pipelines.

Instead, due to the heterogeneity of the sequencing data from different platforms, we used the methods best adapted to each platform, e.g., for mapping, and used comparable stringency parameters whenever possible.