Sentences with phrase «sequence data with»

In addition, generating sequence data with sufficient coverage will allow us to better understand the minor variants that exist as quasispecies within a population.

The first time he released genome - sequencing data with no restrictions, another scientist wrote within hours to tell him that there was a glitch in the database: Anthrax sequences had slipped in with those of the organism they were sequencing.

His primary research interests are bioinformatics, computational biology, machine learning, and integrative analysis of high throughput sequencing data with an emphasis on regulatory genomics and epigenomics.

Not exact matches

Participants in United Therapeutics» clinical trials now have their genomes sequenced and researchers at the company plan to correlate patient outcomes with that genomic sequence data.

With a trillion gigabytes of patient data collected from devices, EHRs, labs, and DNA sequencing, alongside surrounding factors such as weather, geo - location, and viral outbursts taken into account, computers learn quickly, and they learn everything.

For now, the partnership Wojcicki's company has made with Genetech is fairly contained in scope: The two companies will work together to generate sequencing data for the roughly 3,000 spit samples 23andMe has collected from Parkinson's patients in an attempt to identify new treatments for the disease.

The collection of that data — the genetic sequences of 160,000 citizens, along with their medical and genealogical records — was made possible by the Icelandic government, and the storage and analysis of that data was overseen by deCode, a Reykjavík - based human genetics outfit that, since its founding in 1996, had struggled to stay afloat financially.

Onavo sends anonymized data to Facebook on what apps consumers have installed, how frequently they open those apps, how long they linger inside them, and the sequence throughout the day of consumers» app usage — information that functions as an early - detection system on whether an app is gaining popularity, according to the people familiar with the company's activities.

Produced in extensive consultation with NASA scientists, NOVA takes data from earth - observing satellites and transforms it into dazzling visual sequences, each one exposing the intricate and surprising web of forces that sustains life on earth.

Now an enduring individual with personal integrity (as either an ideal or an accomplishment) is an event - sequence any of whose member events has essential data deriving from antecedent and consequent members of the sequence.

He argues that whole genomes will not only provide more data for building trees, but will also enable researchers to study the evolution of regulatory sequences, transposable elements, and other aspects of the genome that are not covered with OpenWings sequencing.

Moreover, data collected from whole - genome sequencing showed that Ata's molecular composition aligned with that of a human genome.

Brains of individuals who died with Huntington's, Parkinson's or no neurological condition were analyzed using sequencing technology that provides a data readout of the activity of all genes in the genome.

Using a mix of live - action sequences, animation and satellite data, the NASA - produced film Water Falls melds science with art to convey the dynamic nature of the water cycle.

The new platform processes hundreds to tens of thousands of cells per day, providing scalable, sensitive, single - cell sequencing with simple yet powerful data analysis.

He also recommends performing standard bulk - cell sequencing on a portion of the sample, to provide a basis for comparison with the single - cell DNA data.

The link protocol is equipped with self - developed smart analog circuits that can rapidly align the receiver's clock with the arrival of the incoming data, and detects the optical signal sequences to rapidly turn the link system on and off.

He says that HLI's actual data are sound, and he is impressed with the group's novel method of determining age by sequencing the ends of chromosomes, which shorten over time.

Using the genetic data, along with high - quality 3D photographs of the participants» faces, the researchers used an artificial intelligence approach to find small differences in DNA sequences, called SNPs, associated with facial features such as cheekbone height.

In a study that included children and young adults with relapsed or refractory cancer, incorporation of integrative clinical genomic sequencing data into clinical management was feasible, revealed potentially actionable findings in nearly half of the patients, and was associated with change in treatment and family genetics counseling for a small proportion of patients, according to a study in the September 1 issue of JAMA.

With the continual improvement of next - generation sequencing technologies, however, obtaining large molecular data sets is becoming much easier, and much cheaper.

The researchers from Queen Mary University of London sequenced the HAS2 gene in thirteen similar or related mammals, combining the data with DNA sequences extracted from 57 published genomes representing all the major mammal groups.

The new study's lead author, Barbara Wallner, an evolutionary biologist at the University of Veterinary Medicine in Vienna, paired these old, yet meticulously kept data with modern DNA sequencing techniques to investigate the origins of today's horse breeds.

We analyzed 7.2 terabases of metagenomic data from 243 Tara Oceans samples from 68 locations in epipelagic and mesopelagic waters across the globe to generate an ocean microbial reference gene catalog with > 40 million nonredundant, mostly novel sequences from viruses, prokaryotes, and picoeukaryotes.

Much of the data in the study has come out previously, some in earlier papers about the parents of the virus that «reassorted» to make this new H1N1, some in the flood of genetic sequences put into public databases, and some in press interviews with public health agencies and academic investigators.

«By reducing non-Y chromosome reads from our data with flow sorting and the RecoverY technique that we developed, and by using this combination of sequencing technologies, we were able to assemble the gorilla Y chromosome so that more than half of the sequence data was in chunks longer than about 100,000 bases in length,» said Medvedev.

However, based on data now available, we see that the sequence of the 3 billion nucleotides in any individual genome is unique in comparison with the sequence of another individual's genome, while the degree of sequence similarity between the 3 billion nucleotides in any two genomes is remarkably high.

A stopped - flow spectrofluorometer was used to study the kinetics renaturation of nuclease from the acidified form on neutralization, the refolding is fast and the data can be described as a sequence of two first - order processes with half times of about 55 and 350 milliseconds, respectively.

Chemistry PhD candidate Richard Li, computational nano / bio physicist Rosa Di Felice, quantum computing expert and Viterbi Professor of Engineering Daniel Lidar along with computational biologist Remo Rohs sought to apply machine learning to derive models from biological data to predict whether certain sequences of DNA represented strong or weak binding sites for binding of a particular set of transcription factors.

The SC3 tool was then used to analyse single - cell RNA - sequence data from two patients diagnosed with myeloproliferative neoplasm (MPN) blood cancers.

Most if not all large scale genome sequencing projects are funded by agencies that, now usually the NIH with the National Science Foundation, that require you to release your data immediately.

«Exposure to lab environments helps computational biologists have a more intuitive understanding of the data and an easier time planning sequencing experiments; lab scientists familiar with data analysis approaches can provide important insights while interpreting results.»

Over the next year, the company plans to use data from human genomes sequenced with its new machines to develop the statistics needed to evaluate how accurate the data are.

The resulting data set consisted of 45 avian genomes sequenced in part for this project [48 when including previously published species (40 — 42)-RSB- and three nonavian reptiles [American alligator, green sea turtle, and green anole lizard (43)-RSB-(table S1), with details reported in (44 — 52).

The differences between coding versus noncoding trees were not solely due to shorter sequence length of the coding data, because the full coding data set (13.3 million bp for c123) produced a tree with fully supported (100 % BS) relationships that were incongruent with those fully supported in the intron (19.3 million bp), TENT (37.4 million bp without the third codon position), and WGT (322.1 million bp)(Figs. 2 and 5B, and table S3).

They show that about 92 per cent of the population harbors bacteria with a variant of the gene sequence, according to a survey of public genome data from 250 adult humans.

The conflict we observe with other data types (14, 15, 24) can no longer be considered to be due to error from smaller amounts of sequence data (8, 17) nor to differences in concatenation versus coalescence methods (27, 28).

In a test designed to show how the tool would be used in actual practice, Dr. Wang retrospectively tested iCAGES using detailed sequencing data from a patient with lung cancer.

The goal is to show that it is possible to accurately sequence human genomes inexpensively, with the hope that collecting such data will eventually become routine in the clinic.

These differences are not merely due to shorter alignments of the exon and UCE sequences, because each accounted for ~ 25 % of the TENT data, similar in sequence length to the random 25 % subset of the TENT with introns (table S3) that produced a tree with a higher average BS and a topology closer to the full TENT (Fig. 5A and fig.

And Phil Green, a genomicist at the University of Washington, Seattle, who has developed the widely used PHRED and PHRAP programs for assembling sequence data, said that he, too, had come up with a low gene count of about 35,000.

Although some of the findings of the initial multigene studies (8, 17) have since been corroborated with larger sequence (26 — 28) or transposable element (TE) insertion data sets (29), other proposed clades were not supported (27, 28).

Two years ago, Oxford Nanopore Technologies demonstrated a revolutionary new sequencing technology at a meeting for genomicists, but it's taken until now for it to show more data and to begin to share its new cheap, hand - held device with researchers.

Today in Science he and his colleagues report that they've used their technique in conjunction with metagenome sequencing, in which researchers sequence vast swaths of genome data from unknown organisms in the ocean and soil.

Along with representatives from the medical, scientific, and bioethics communities, two representatives of the Lacks family will serve on NIH's newly formed, six - member working group that will review proposals for access to the HeLa full genome sequence data.

The first study to sequence and analyze the entire genome of a HeLa cell line, along with access to its sequence data, has been published Aug. 7 in its final version, by G3: Genes Genomes Genetics, an open - access, scientific journal of the Genetics Society of America.

The new controlled access policy for full genome sequence data from HeLa cells will give the Lacks family the ability to have a role in work being done with the HeLa genome sequences and track any resulting discoveries.

Researchers working with stem cells should follow the example of their colleagues in genetic sequencing and clinical research, setting up global networks for sharing data, materials, and intellectual property, according to a report released today in Washington, D.C..

The new approach will likely continue to grow more powerful with more sequencing data, Preusch says.

In a similar case with a 12 - year - old whose exome was sequenced without any family data, Phevor built on the analysis of VAAST to identify a gene mutation causing the illness, another autoimmune syndrome.