Sentences with phrase «sequence differences between»

These proteins display large sequence differences between themselves (Supplementary Table 1) and they are properly folded, highly stable, active and share the β - lactamase fold11.

Zoghbi's lab meticulously analyzed each gene in this region, systematically eliminating genes based on sequence differences between healthy controls and Rett syndrome patients.

When you are looking for potential SNPs, particularly without a reference genome, you run the risk of identifying sequence differences between duplicated sequences rather than differences between individuals.

Following re-design of the R5 - ZFNs to account for sequence differences between the human and macaque alleles, we found that ZFNs could disrupt both alleles with reasonable efficiency in macaque CD4 + T cells.

DNA sequence differences between the pectate lyase genes from the cultivated tomato and S. pennellii can then be used as markers to screen the progeny from this cross.

The study, led by Dr Chris Tyler - Smith of the Wellcome Trust Sanger Institute, analysed sequence differences between the Y chromosomes of more than 1200 men from 26 populations around the world using data generated by the 1000 Genomes Project.

NYGC computational biologists and members of the Simon Laboratory at The Rockefeller University discussed the possibility of using a series of computer algorithms to search for sequence differences between the tumor samples and samples of healthy liver tissue.

Even if we document all of the perhaps 40 million sequence differences between humans and chimps, what do they mean?

«The sequence difference is larger than the average sequence difference between humans and chimps, so we estimate it occurred at least 4 million years ago,» Andersson explained.

Not exact matches

According to the latter, each religion is placed in a sequence according to some qualitative differences between them arbitrarily established.

The second is slightly more friendly to non-science trained people but may still require some referencing of other sources to understand various details (e.g. the difference between mitochondrial and nuclear genetic sequencing).

The difference between the two is that the living God becomes Incarnate afresh in each moment of the life of Jesus (or of ourselves), whereas the experiences of Jesus «prehended» by God into himself — Jesus» resurrection and ascension — form a finite sequence that terminated on Calvary.

With the Premier League table still so tight at the bottom, any positive sequence of results could spell the difference between mid-table comfort and squeaky bum time between now and the end of the season.

In this standard view, the genetic differences between any two individuals are due to slight differences in the sequence of their genes that mean that the genes «spell out» slightly different proteins.

The researchers compared the differences between the two sets of sequences to reconstruct how the H7N9 virus evolved through various species of birds and to determine the origin of genes.

When it came to memorizing sequences of three - digit numbers, the difference between the memory contestants and the control subjects was, as expected, immense.

As you said it is an extremely small number of differences that you find genetically between humans and chimps, but it is an extremely important one, and what seems to make it so important is that a lot o these differences seem to affect what are in effect regulatory sequences.

They used sequences of maternally inherited mitochondrial DNA and «microsatellite genotypes,» or DNA profiles, to both describe the genetic differences and outline migratory connections between both breeding and feeding grounds.

Because the genome for Dictyostelium has been sequenced, researchers are already deeply immersed in teasing apart different genes and traits that might help explain the differences between farmers and nonfarmers and how the symbiosis might have evolved in the first place.

And so we were expecting that, pretty much you explained the difference between these two proteins actually, in the protein sequence, and some changes have taken place there.

Deep sequencing of isolates taken from a single patient carrying MRSA for the longest period revealed that although all isolates were of the same clade, there were small genetic differences between them, suggesting bacterial diversity within a single carrier.

To determine how tightly the probe binds, researchers heat it up to shake the probe loose; however, often there's only a few degrees difference between the «melting» temperature of a probe bound to the exact target sequence and one where there is a minor discrepancy.

Tao's proof, posted online September 18 at arXiv.org, shows that the difference (or discrepancy) between the quantities of two elements within certain sequences can grow without bound, even if someone does the best possible job of minimizing the discrepancy.

The differences between male and female iPS cells are most pronounced for one of the key processes in the field of epigenetics: DNA methylation, a modification that changes the activity of a DNA segment without changing its sequence.

She wrote her doctoral thesis on how abalone grow their rough outer shells and pearl - like inner shells, the main difference between the two being a simple shift in protein sequences.

Their to - do list includes determining whether the fossils might contain proteins or DNA suitable for sequencing, reconstructing the environment the hominins lived in, and studying differences between males and females.

By analyzing the similarities and differences between DNA sequences of different organisms, biologists can infer relatedness between them.

The differences between coding versus noncoding trees were not solely due to shorter sequence length of the coding data, because the full coding data set (13.3 million bp for c123) produced a tree with fully supported (100 % BS) relationships that were incongruent with those fully supported in the intron (19.3 million bp), TENT (37.4 million bp without the third codon position), and WGT (322.1 million bp)(Figs. 2 and 5B, and table S3).

When researchers sequenced the chimpanzee genome in 2005, the biggest difference between it and the human genome was the extinct PtERV1 retrovirus, which inserted its DNA into the cells it infected like HIV does today.

(Because of the strong sequence similarities between the two genes, the scientists have not yet been able to turn off one without the other, so differences between their functions are still unclear.)

Translating the differences between gene sequences into a date for their divergence, the researchers conclude that the various forms of RRM2P4 last shared a common ancestor about two million years ago — around when H. erectus migrated from Africa into Asia.

Significant differences were also discovered between the centenarians and the two control groups when their genotype frequencies were compared, in other words, the proportion of individuals with a specific gene sequence.

Now, the complete genome sequence of more than 200 Atlantic cod was used to investigate the genetic difference between the males and the females in great detail.

Using both DNA sequencing and morphology, along with differences in plumage, breeding biology, vocalisation, habitat, distribution, dispersal and migration it was possible to show the differences between the two species.

Esparza stresses that no one really knows how the differences between the various subtypes — in the sequence of their env gene, and structure of their gp120 — will affect people's immune responses.

Our study provides hints that at least some of the apparent sub-types in ME / CFS could be due to differences between DNA sequences in the patients, even though we have no evidence that particular mitochondrial genomes lead to increased susceptibility to the disease itself.

If a store, clinic or health center does not know or understand the difference between personal genetics (i.e. the sequence of your genes) and epigenetics, you may want to think twice before trusting them with your health or money.

This expertise is coming into its own in the internationally collaborative 1000 Genomes Project: «While the genome sequence is what makes us human, it's the differences in the genome sequences between all of us that are really the interesting part,» says Paul.

Differences between individual DNA sequences provide the basis for human genetic variability.

Sequence polymorphisms in this gene between susceptible and resistant strains were identified that may account for the difference in phenotype.

Findings showed subtle differences between the viral genetic sequences taken from the vaccinated individuals, compared to the placebo recipients.

There are also many other differences in the number or coding sequences of ankyrin repeat genes between wMel strain genomes and wAu [21], [49](see also [15] and [48] for sequence of wMelCS).

wAu genome is not sequenced, however, several differences between the genome of wAu and wMelCS are described.

Experts trace an individual's DNA back through history, looking for differences in the DNA sequences between the two copies of his or her genome.

From genomic and epigenomic sequences from a subset of the populations, we see changes in methylation patterns between the evolved populations over-represented in some functional categories of genes, which is consistent with some of these differences being adaptive.

In this study, we have examined the differences between the four commonly used whole genome next - generation sequencing platforms, Illumina's HiSeq2000, Life Technologies» SOLiD 4 and 5500xl SOLiD, and Complete Genomics» technology.

By SNP analysis, single nucleotide differences between the sequences of 22Rv1 - associated XMRV and XMRV genomes detected in prostate cancer tissues [VP35, VP42, and VP62 (2006)-RSB-(red lollipops) are corrected by the deep sequencing coverage data (black lollipops).

The mean sensitivity for ONE - level of embedding (LoE) sequences was also significantly higher than TWO - LoE sequences, but the difference in bias between the two levels of embedding was not significant (see Fig. 2 and Table 2).

One problem is the difference between the plausible fictionalizations and the implausible ones, including an entire ending chase sequence that's obviously concocted, as well as comeuppance to the plutocrat cheapskate.

A sampling of these awards include Best Depiction Of Nudity, Sexuality, or Seduction, awarded to Scarlett Johansson and Joaquin Phoenix for their digital lovemaking in «Her,» as well as the Most Memorable Moment Award, which went to «12 Years A Slave» for the Solomon hanging sequence, and the Most Egregious Age Difference Between The Leading Man and The Love Interest, which went to Michael Douglas and Bre Blair for «Last Vegas.»