Sentences with phrase «sequence of amino acids»

The sequence of these amino acids determines the specific function of a protein.

The sequence of amino acids is so detailed, that any change or mishandling of it will change what it is.

The sequence of amino acids in a protein molecule is defined my the sequence of the gene for that protein.

The protein's propensity to huddle into one kind of spherical arrangement vs. another appears to depend on its sequence of amino acids.

The beauty of this Y - shape molecule is that although the basic structure remains the same, millions of slight variations can be produced by changing the sequence of amino acids in the protein strands at the ends of the two arms of the «Y» molecule.

The sequence of bases determines the instructions (genetic code) for the sequence of amino acids that form proteins.

The particular sequence of amino acids in the chain is what makes one protein different from another.

Protein the building blocks of cells — each protein molecule is composed of its own unique sequence of amino acids (there are 20 different kinds of amino acids in the human body).

protein: A molecule made up of a sequence of amino acids (there are 23 different amino acids).

Delbrück's summer course on bacteriophages in 1945 at Cold Spring Harbor in New York set in motion the chain of events that led to understanding the genetic code by which the sequence of the nucleotides in DNA is translated into the sequence of amino acids in a protein.

IT TURNS OUT THAT the sequence of amino acids that makes up the amyloid - beta protein isn't unique to humans.

A comparison of the sequence of amino acids in NGF with that of several other polypeptides by William A. Frazier of Washington University revealed that NGF and insulin have certain sequences in common.

With the large quantities of NGF made available by their technique Ruth Hogue Angeletti and Ralph A. Bradshaw of the Washington University School of Medicine were able to determine the sequence of amino acids in the protein.

Silent mutations occur when the change of a single DNA nucleotide within a protein - coding portion of a gene does not affect the sequence of amino acids that make up the gene's protein.

Then he used a computer to compare the string of amino acids making up the protein to the sequence of amino acids in all other known proteins.

Prions can exist as distinct strains — proteins that have the same sequence of amino acids but misfold in different ways and have distinct biological behaviours, much as different strains of a pathogenic virus can be aggressive or weak.

Starting in the late 1980s, their labs revealed steps in how the endoplasmic reticulum, the cell's factory for processing secreted and membrane proteins, deals with proteins whose linear sequence of amino acids hasn't folded into a proper 3D shape.

During this crucial step, messenger RNA (mRNA), which is a RNA copy of a gene's recipe for a protein, is translated by the cell's ribosome into the sequence of amino acids that will make up a newly synthesized protein.

Dr. Montelaro and his colleagues found that a particular sequence of amino acids on the tail end of HIV allow the virus to «punch into» and infect cells.

They found that one small section of the toxin is «highly conserved,» meaning that its sequence of amino acids is identical to the same sequence in other Clostridium species.

«Genes code for the sequence of amino acids in proteins, and some are involved in the regulation of the expression of other genes,» he says.

As the authors of the new research explain: «There are three main levels of analysis in the study of proteins: the first is the sequence of amino acids, the second is the three - dimensional structure that these filaments take on a very short time after they are synthesized, while the third regards their function.

The shape in which a protein naturally folds is known as its native state, which is determined by its sequence of amino acids.

Biochemists found out how to determine the sequences of amino acids in proteins.

The major function of DNA is to encode the sequence of amino acid residues in proteins, using the genetic code.

These RNA - binding proteins include sequences of amino acids that bind to one of the ribonucleotide bases or «letters» that make up RNA sequences — adenine (A), thymine (T), uracil (U), and guanine (G).

It persists, in large part, due to continual changes in the sequence of amino acid «building blocks» that make up the viral protein hemagglutinin, enabling it to avoid recognition and removal by immune system antibodies.

Additionally, colleagues from the Washington University in St. Louis predicted the sequences of the amino acids responsible for Sup35 sensing changes in the cytoplasmic pH value.

After designing the chemical building blocks of peptides, the researchers used the supercomputer Mira, with its 10 petaflops of processing power and more than 780,000 cores, to model scores of potential shapes, or conformations, that specific backbone sequences of amino acids might take.

With no candidate targets, the team took an objective approach by applying a peptide phage library to MDSCs, which permitted mass screening for candidate peptides — short sequences of amino acids — that bind to the surface of the MDSCs.

Proteins are defined by their unique sequence of amino acid residues; this sequence is the primary structure of the protein.

Not exact matches

biochemical evidence such as Cytochrome - cyto - C is just one of the thousands of sequences and is not proof of common ancestry, as there are more variations than similarities in the genetic code, on the other hand a study of the amino acid make - up reveals that man is closer to lamprey than are fish.

There is no such «direct» evolution: animals, bacteria, and algae have a common ancestor from which they have diverged, as can be shown by aligning and comparing amino acid sequences of proteins and nucleotide sequences of homologous ribosomal RNA molecules that are found in both bacteria and vertebrates.

I love biology, every pain staking detail of DNA - one mess up in an amino acid sequence and you get sickle - cell anima, or the proteins don't function correctly.

They use this peptide «skeleton» to generate thousands (or even hundreds of thousands) of possible amino acid sequences that could support stable interactions for that conformation.

The open reading frame of the sequenced clone coded for 97 amino acids, including the known amino acid sequence of this polypeptide.

He identified a short stretch of its sequence that repeatedly coded for leucine, an amino acid.

«We were looking at the amino acid sequences of T cell receptors when Tomer asked what the corresponding epitope was for a particular receptor,» Thomas said.

The tools included TCRdist, which researchers used to calculate the similarity and differences of key features of T cell receptors, such as amino acid sequences in important regions for antigen recognition.

An antibody to a peptide synthesized according to deduced amino acid sequence reacts specifically with the alpha subunit of Gs.

They retained, for example, the amino acid residues that bind to G - tract RNA, and the researchers confirmed that, like their mammalian counterparts, each RNA - binding domain of Glo can bind to this type of RNA sequence.

Molecular geneticist Cheng Chi Lee, developmental biologist Gregor Eichele, and their co-workers at the Baylor College of Medicine in Houston have isolated a gene in mice and humans that shares 44 % of the amino acid sequence of the period (per) gene of the fruit fly Drosophila melanogaster.

To create their code, the researchers tested out many amino acid combinations and found a particular set of amino acids that will bind each of the four bases at any position in the target sequence.

A sequence of aspartic amino acids that is known as the Ca2 + bowl, and is located within the second of the tandem RCK domains, creates four Ca2 + binding sites on the outer perimeter of the gating ring at the «assembly interface» between RCK domains.

The research team used molecular modeling and knowledge of hemagglutanin's structure to identify mutations that would change the protein's amino acid sequence and cause a switch to human specificity.

It is not unusual for the program to create tens of thousands of model structures for an amino acid sequence and then identify the ones with lowest energy state.

Naturally occurring peptides can be composed of 20 different amino acids, so there is a great deal of possible variation in their sequences.

The genetic code is the set of rules by which information encoded in genetic material (DNA or RNA sequences) is translated into proteins (amino acid sequences) by living cells.

Conventional wisdom had suggested that GSK - 3 phosphorylates proteins that contain a specific amino acid sequence, but the new phosphoproteome showed that the majority of proteins whose phosphorylation depended on GSK - 3 did not contain this sequence.

They found that the proteins of prokaryotes (the group of organisms that includes bacteria and blue - green algae) tended to have sequences of about 150 amino acids, or a multiple of that number, while the proteins of the eukaryotes (which account for all other organisms) had amino acid sequences in multiples of around 125.