Sentences with phrase «sequence studies over»

We believe that this is an important advantage for conducting large - scale whole sequence studies over the next couple of years,» said Kari Stefansson, CEO of deCODE.

All seven were located in or near complement genes (that's «complement» as in the innate immune system complex), which had been implicated in AMD by sequencing studies over the past couple of years.

Not exact matches

For the study, they analyzed the genetics of more than 1,500 hemagglutinin (HA1) sequences collected over the course of seven years.

Through a variety of «high tech» approaches, including the isolation of monoclonal antibodies from single B cells and ultra-deep sequencing of shifting viral populations over more than three years of infection, the researchers studied one woman who developed potent broadly neutralizing antibodies.

They specifically studied the length of telomeres (repeated DNA sequences) on the ends of chromosomes in leukocytes (white blood cells); the protective caps are believed to be markers of biological aging, because they shrink over time.

The team also looked at changes in the genetic sequence of the Zika NS1 protein over time, noted David L. Akey, a research scientist in Smith's lab and the study's other lead author.

Genome sequencing also revealed that MRSA clades were dynamic in the ICU over the three - month period, with some clades more prevalent early in the study and others later.

In the study, Plasmodium falciparum parasites were kept dividing in human blood for over a year in the laboratory, with the full parasite genome being sequenced regularly.

Comparing those sequences from many different species could reveal evolution's handiwork over geological time, much as studies of ancient DNA do today.

Despite their importance, these repetitive sequences are often skipped over and not analyzed in genome studies.

This sequence of events contrasts with the case of a S. aureus strain from pigs, Fitzgerald points out, since a study in 2012 revealed that MRSA ST398 strains evolved the ability to resist methicillin before they crossed over into humans.

A new study finds up to 250 regions where the reference genome sequenced over 13 years may be missing information

Dr. Donovan Bailey, senior author of the study and professor at New Mexico State University, said this approach has several advantages over previously established methods for enriching either nuclear or organellar DNA for genome sequencing.

«To date we have over 350 phenotypes enrolled in our study with over 3,200 patient samples having undergone exome sequencing.

The study, which was based on over seven billion DNA sequences and which is published in Nature Communications, found no genetic traces of viruses in these forms of cancer.

This $ 240 million initiative aims to sequence 200,000 genomes over the next four years, making it among the largest sequencing studies in the world.

For the study, the team analyzed viral genomic sequences from 232 patient samples collected over the 7 - month spread of the disease in Sierra Leone, along with 86 genome sequences reported earlier in the epidemic.

Over the past decade due to the deep - sequencing technologies, we have studied the characterization of nucleic acid alterations in a wide range of cancers generating a large body of information on how cancer develops and evolves.

It's the kind of cohort that genetics researchers are currently salivating over, especially in the era of large - scale sequencing studies.

As a result, we're seeing exome and genome sequencing studies published all over the place, not just in genetics / genomics journals but also many that focus on specific tissues (e.g. blood) or diseases (e.g. cancer, metabolic diseases, vision disorders, you name it).

Within this consortium, she has conducted genome - wide association scans for over 75,000 participants and has undertaken one of the first large - scale whole - genome sequencing studies for colorectal cancer, sequencing the whole genomes of 2,000 patients with colorectal cancer and 1,000 healthy control participants.

All of this points to the heart of the problem with genotyping over sequencing studies: many of the most interesting classes of variation are overlooked.

In a study published today, scientists at deCODE genetics use genomic and genealogical data from across the population of Iceland over many decades to show that people who carry sequence variations linked to higher levels of education have fewer children than average...

While whole genome sequencing studies have failed to identify coding mutations in 40 % of the cases, there is evidence from recent efforts to annotate the non-coding sequence that over 80 % of the genome is biochemically active.

Recent studies using rapid sequences of faces have found that perception of face identity is biased towards recently seen faces, promoting identity - invariance over time, and this has been extended to perceived face attractiveness.

This case study shows a 4 - day lesson sequence that was taught in 10 first - year mathematics classes in this school over a 4 - week period.

The Reconstruction Era and the Fragility of Democracy is aligned with college and career readiness standards and unfolds over 16 lessons, sequenced according to the underlying pedagogy — or scope and sequence — that shapes every Facing History and Ourselves course of study.

Observational study revealed that positioning each painting horizontally and flipping over every other painting in the sequence gave a zig - zag, out of sequence oddity that was key to dialogue and discovery.

[UPDATE, 12/2: The Computational Legal Studies group has developed an animation (abov) showing the sequence of climate emails over 13 years.

The study then examined the participants» DNA, specifically the length of their telomeres, which are — he explained — repetition sequences of DNA at the end of chromosomes that shorten as one gets older, «like the plastic tabs on shoelaces that fray over time».

However, results from his systematic study proved that couples did behave with tremendous regularity over time and science could, indeed, identify sequences of interactions among sets of happy and unhappy couples.

This study identified temporal sequencing in the associations between family support and depressive symptoms over the course of adolescence for youth in Ghana.