A system for automated detection of homologs among the annotated genes of several completely
sequenced eukaryotic genomes.
Not exact matches
The EBP would focus on the natural world, providing a better understanding of biodiversity by first
sequencing in great detail the DNA of a member of each
eukaryotic family (about 9000 in all) and eventually generating coarser
genomes for the other eukaryotes.
Our method, based ideally on 20x and 50x of NaS and Illumina reads respectively, provides an efficient and cost - effective way of
sequencing microbial or small
eukaryotic genomes in a very short time even in small facilities.
As is often the case for yeast, the ability to
sequence and analyze whole
genomes at very deep coverage has yielded broad insights on
eukaryotic genome evolution.
The random BAC fingerprinting technique has rapidly become the method of choice for mapping and
sequencing the comparatively large
genomes of other
eukaryotic organisms, including humans.
IRES was originally discovered in poliovirus RNA, where it promotes translation of the viral
genome in
eukaryotic cells.1, 2 Since then, a variety of IRES
sequences have been discovered - many from viruses, but also some from cellular mRNAs.
The ability to quickly obtain accurate
genome sequences of
eukaryotic pathogens at low costs provides a tremendous opportunity to identify novel targets for therapeutics, develop pesticides with increased target specificity and breed for resistance in food crops.
Oxford Nanopore
sequencing, hybrid error correction, and de novo assembly of a
eukaryotic genome
With the current
sequencing technology and bioinformatics tool set, we are able to deliver an
eukaryotic fungal
genome at low cost within a week.
Here, we present the first report of the ~ 54 MB
eukaryotic genome sequence of Rhizoctonia solani, an important pathogenic fungal species of maize, using nanopore technology.
We have
sequenced the
genome of the endangered European eel using the MinION by Oxford Nanopore, and assembled these data using a novel algorithm specifically designed for large
eukaryotic genomes.
Using MinION nanopore
sequencing to generate a de novo
eukaryotic draft
genome: preliminary physiological and genomic description of the extremophilic red alga Galdieria sulphuraria strain SAG 107.79