Sentences with phrase «sequenced key gene»

During the 1990s, a team led by Jeffery Taubenberger at the Armed Forces Institute of Pathology in Washington, D.C., sequenced key gene fragments of the 1918 flu strain, recovered from frozen victims found in the Alaskan permafrost and in archived autopsy material.

Not exact matches

Biologists now know that the genome sequence holds only a small part of the answer, and that key elements of development and disease are controlled by the epigenome — a set of chemical modifications, not encoded in DNA, that orchestrate how and when genes are expressed.

The team sequenced the gene that codes for the NaV1.7 channel in mole rats, and compared it with SCN9A — a key gene in the human version of the channel.

To determine how similar a person's fingertip bacteria are to bacteria left on computer keys, the team took swabs from three computer keyboards and compared bacterial gene sequences with those from the fingertips of the keyboard owners.

With the completion of the first phase of the Human Genome Project in 2000, and the advent of sequencing technologies that can detect gene variations such as single nucleotide polymorphisms (SNPs), for the first time scientists have the tools in hand to find the key immune genes and genetic networks that play roles in vaccine response.

Among the key elements engineers need to get an organism such as E. coli to make a protein from a synthesized gene are extra sequences such as promoters (to help the cell make RNA from DNA) and ribosome binding sites (or RBS, which the cell needs to make proteins from the RNA).

In particular, the comparison of gene sequences in large numbers of patients and controls will be a key step in strategies for disease gene identification.

Researchers have sequenced the genomes of all 15 species of Darwin's finches, revealing a key gene responsible for the diversity in the birds» beaks.

After the sections of DNA sequence have been assembled into a complete genome sequence we need to identify where the genes and key features are, but how do we do this?

April 2012 - New research: Illuminating embryonic stem cells Collaboration between two EU funded projects «Heroic» and «EuroSyStem», has provided new insights into embryonic stem cells The teams used next generation sequencing technology to examine two key properties of the cells that influence their identity and behaviour: gene expression and gene regulation.

Scientists have now sequenced the genome of the Mexican axolotl, and have identified a few key genes hidden amongst its extremely complex genetic blueprint that shed some light on its remarkable regeneration capabilities.

deCODE has identified key variations in the sequence of the genome conferring increased risk of major public health challenges from cardiovascular disease to cancer, and employs its gene discovery engine to develop DNA - based tests to assess individual risk of common diseases; to license its tests and intellectual property to partners; and to provide comprehensive, leading - edge contract services to companies and research institutions around the globe.

The SIGMA project aims to develop novel biomedical approaches to treat this devastating disease by applying powerful sequencing technologies to discover the genes and key pathways underlying common varieties of cancer.

In exploring how proteins interact with crucial DNA sequences to regulate gene activity, researchers have shed light on key biological...

By comparing the promoter sequences of expressed with non-expressed OR and VR genes and pseudogenes, it may now be possible to identify key genomic motifs that control receptor choice.

Viral gene sequences from an enlarged set of about 200 Epstein - Barr virus (EBV) strains including many primary isolates have been used to investigate variation in key viral genetic regions, particularly LMP1, Zp, gp350, EBNA1 and the BART miRNA cluster 2.

Over 4 million coding mutations are described in v78 (September 2016), combining genome - wide sequencing results from 28 366 tumours with complete manual curation of 23 489 individual publications focused on 186 key genes and 286 key fusion pairs across all cancers.

They use natural plant centromeres (a key part of chromosomes needed for their inheritance), promoters (gene activation sites), and gene - termination sequences to assemble linear or circular minichromosomes that contain at least a dozen genes that can improve crops by promoting traits like pest and disease resistance.

Since gene sequencing technology became a key part of the medical and health sciences around a little over a decade ago, we now understand a lot more about the importance of genetic variations.

Given advances in the rate of DNA sequencing, the full genetic code of key crops grown in the two regions could be built very quickly, and the identities and function of their genes could be determined by relying on similarities to the existing Arabidopsis, rice, and sorghum sequences and the emerging maize sequence.