«The elephant results revealed noncoding
sequences in the human genome that we predict may control gene activity and reduce the formation of mutations and cancer.»
Richard Walker of the University of South Florida College of Medicine in Tampa and his team are comparing the DNA of «teen baby» Brooke Greenberg, from Baltimore, Maryland, with that of her three healthy sisters, her parents and standard human DNA
sequences in the human genome database.
The researchers were searching for archaic DNA
sequences in those human genomes at frequencies much higher than would be expected if those genes weren't doing people any good.
Peter and his team discovered
sequences in the human genome that when converted into small double - stranded RNA molecules trigger what they believe to be an ancient kill switch in cells to prevent cancer.
The researchers searched hundreds of molecules for potential partners of α - catenin and turned up a new protein known only by
its sequence in the human genome database: ARHGAP10.
«Discovery and typing of polymorphic non-deletions of ancestral hominid
sequence in the human genome»
Not exact matches
Venter, who is one of the first people to
sequence the
human genome, co-founded the company
in effort to discover early genetic markers for a variety of disorders.
The commercialization of DNA
sequencing (the reading of an organism's code) and synthesis (the writing of that code) has accelerated since the mapping of the
human genome was completed
in 2003.
Dec. 18, 2013 — The most complete
sequence to date of the Neanderthal
genome, using DNA extracted from a woman's toe bone that dates back 50,000 years, reveals a long history of interbreeding among at least four different types of early
humans living
in Europe and Asia at that time, according to University of California, Berkeley, scientists.
In June 2000 he and Craig Venter of the rival commercial project were able jointly to announce the entire
sequencing of the
human genome.
A
human - chimp comparison revealed some 35 million mutations
in the single units of the overall
sequence and also found about 5 million additions to or subtractions from the
genome involving chunks of DNA
sequence.
In sequencing of the
human genome, we learned that diseases rarely correlated to specific
human genes.
All the technologies for
sequencing the
human genome have been developed
in this country.
To determine how the cells switch from one type to another, they took three
human uterine carcinosarcoma samples and
sequenced the
genomes of cells
in two parts of each tumor: the carcinoma and sarcoma components.
The newly
sequenced genome of the plague - causing bacterium Yersinia pestis suggests
human adaptations are what have kept this disease
in check
An international team led by researchers with the Lawrence Berkeley National Laboratory (Berkeley Lab) has developed a new technique for identifying gene enhancers —
sequences of DNA that act to amplify the expression of a specific gene —
in the
genomes of
humans and other mammals.
In February, researchers published the first ancient American human genome, sequencing DNA from the remains of a boy known as Anzick - 1, who was buried about 12,600 years ago in what is now western Montan
In February, researchers published the first ancient American
human genome,
sequencing DNA from the remains of a boy known as Anzick - 1, who was buried about 12,600 years ago
in what is now western Montan
in what is now western Montana.
Thanks to powerful gene -
sequencing techniques developed
in the past two decades during the race to decode the
human genome, researchers are beginning to reconstruct what our ancestors» microbiomes looked like, potentially going back thousands of years.
Now that the whole Neanderthal
genome has been
sequenced, Harvard geneticist George Church thinks a clone could be gestated
in a
human surrogate mother.
The
Human Genome Project, which sequenced the 3 billion pairs of nucleotide bases in human DNA, was a piece of cake in comparison: Epigenetic markers and patterns are different in every tissue type in the human body and also change over
Human Genome Project, which
sequenced the 3 billion pairs of nucleotide bases
in human DNA, was a piece of cake in comparison: Epigenetic markers and patterns are different in every tissue type in the human body and also change over
human DNA, was a piece of cake
in comparison: Epigenetic markers and patterns are different
in every tissue type
in the
human body and also change over
human body and also change over time.
In addition to
sequencing the woolly mammoth
genome, Hendrik has reconstructed the diets of extinct giant sloths, debunked a hypothesis about the origin of
human immunodeficiency virus (HIV) and
sequenced the
genome of the bacterium that caused Black Death.
An analysis of the HPV16
genome from 5,570
human cell and tissue samples revealed that the virus actually consists of thousands of unique
genomes, such that infected women living
in the same region often have different HPV16
sequences and variable risks to cancer.
Data published by the International
Human Genome Sequencing Consortium indicate that somewhere between 113 and 223 genes present in bacteria and in the human genome are absent in well - studied organisms — such as the yeast Saccharomyces cerevisiae, the fruit fly Drosophila melanogaster and the nematode Caenorhabditis elegans — that lie in between those two evolutionary extr
Human Genome Sequencing Consortium indicate that somewhere between 113 and 223 genes present in bacteria and in the human genome are absent in well - studied organisms — such as the yeast Saccharomyces cerevisiae, the fruit fly Drosophila melanogaster and the nematode Caenorhabditis elegans — that lie in between those two evolutionary ext
Genome Sequencing Consortium indicate that somewhere between 113 and 223 genes present
in bacteria and
in the
human genome are absent in well - studied organisms — such as the yeast Saccharomyces cerevisiae, the fruit fly Drosophila melanogaster and the nematode Caenorhabditis elegans — that lie in between those two evolutionary extr
human genome are absent in well - studied organisms — such as the yeast Saccharomyces cerevisiae, the fruit fly Drosophila melanogaster and the nematode Caenorhabditis elegans — that lie in between those two evolutionary ext
genome are absent
in well - studied organisms — such as the yeast Saccharomyces cerevisiae, the fruit fly Drosophila melanogaster and the nematode Caenorhabditis elegans — that lie
in between those two evolutionary extremes.
And with the recent unveiling of the
human genome sequence — to say nothing of the new drugs that are being tested every day — those working
in the patent field are busier than ever.
Erwin compares the endeavor to the
Human Genome Project,
in which scientists mapped the
sequence of our genes.
In 1991, technology was developed that permitted «shot gun»
sequencing, the identification of short DNA
sequences scattered virtually at random throughout the 100,000 or so genes of the
human genome.
If all this sounds wildly implausible, bear
in mind that the idea of
sequencing an entire
human genome in days seemed nigh on impossible just a few years ago.
And
in the United States, the National
Human Genome Research Institute in Bethesda, Maryland, recently funded three Mendelian Disorders Sequencing Centers that will apply genome sequencing to diagnosing thousands of patients with a wider range of rare diseases, including intellectual disability and developmental
Genome Research Institute
in Bethesda, Maryland, recently funded three Mendelian Disorders
Sequencing Centers that will apply genome sequencing to diagnosing thousands of patients with a wider range of rare diseases, including intellectual disability and developmen
Sequencing Centers that will apply
genome sequencing to diagnosing thousands of patients with a wider range of rare diseases, including intellectual disability and developmental
genome sequencing to diagnosing thousands of patients with a wider range of rare diseases, including intellectual disability and developmen
sequencing to diagnosing thousands of patients with a wider range of rare diseases, including intellectual disability and developmental delay.
«We explored the opportunity of using sperm RNA elements as a predictor of
human health, with applications at the fertility clinic that would go hand - in - hand with the new neonatal intensive care unit genome sequencing to better health outcomes,» said Dr. Krawetz, associate director of the C.S. Mott Center for Human Growth and Develop
human health, with applications at the fertility clinic that would go hand -
in - hand with the new neonatal intensive care unit
genome sequencing to better health outcomes,» said Dr. Krawetz, associate director of the C.S. Mott Center for
Human Growth and Develop
Human Growth and Development.
The publication of the
human genome in 2001 revealed its
sequence — the significance of which remains a mystery.
Using advanced
sequencing technologies, University of Oklahoma anthropologists demonstrate that
human DNA can be significantly enriched from dental calculus (calcified dental plaque) enabling the reconstruction of whole mitochondrial
genomes for maternal ancestry analysis — an alternative to skeletal remains
in ancient DNA investigations of
human ancestry.
Encased
in ice for 4,000 years, a clump of prehistoric
human hair gave up its secrets to the University of Copenhagen's Eske Willerslev, the first researcher to
sequence an ancient
human genome.
As the cost of
sequencing the
human genome has plummeted
in recent years, many medical researchers have touted the potential of personalized medicine — exotic therapies and synthetic drugs that are tailored to our individual genetic makeup.
Along the way, the hope is that the project will transform the technology of neuroscience —
in the same way that the
Human Genome Project (HGP) helped take genome - sequencing from pipe dream to everyday reality — and ultimately revolutionise our understanding of brain fun
Genome Project (HGP) helped take
genome - sequencing from pipe dream to everyday reality — and ultimately revolutionise our understanding of brain fun
genome -
sequencing from pipe dream to everyday reality — and ultimately revolutionise our understanding of brain function.
In - depth analysis of the human body's microflora has been possible only in the past few years — a by - product of the same new gene sequencing techniques that have allowed scientists to cheaply and accurately identify the DNA of the human genom
In - depth analysis of the
human body's microflora has been possible only
in the past few years — a by - product of the same new gene sequencing techniques that have allowed scientists to cheaply and accurately identify the DNA of the human genom
in the past few years — a by - product of the same new gene
sequencing techniques that have allowed scientists to cheaply and accurately identify the DNA of the
human genome.
«Once we can build that sort of database for the
human organism, it helps us much better understand disease, how to diagnose disease, how better to treat disease,» says Richard Wilson, the director of the
Genome Sequencing Center at Washington University
in St. Louis.
Kanost and the Kansas State University team prepared and purified the DNA of the tobacco hornworm and sent the samples to the Baylor College of Medicine
Human Genome Sequencing Center in Houston, which performed the genome seque
Genome Sequencing Center in Houston, which performed the genome s
Sequencing Center
in Houston, which performed the
genome seque
genome sequencingsequencing.
In one of their most challenging
human DNA projects to date — no British individual this old has ever had their
genome sequenced — the Natural History Museum's ancient DNA lab's Professor Ian Barnes and Dr Selina Brace carried out the first ever full reading of Cheddar Man's DNA.
All that changed this month, with the publication of a 400,000 - year - old mitochondrial
genome sequenced from the remains of an early
human found
in a cave
in Spain.
So declared President Bill Clinton
in the East Room of the White House on June 26, 2000, at an event held to hail the completion of the first draft assemblies of the
human genome sequence by two fierce rivals, the publicly funded international Human Genome Project and its private - sector competitor Celera Genomics of Rockville,
human genome sequence by two fierce rivals, the publicly funded international Human Genome Project and its private - sector competitor Celera Genomics of Rockville
genome sequence by two fierce rivals, the publicly funded international
Human Genome Project and its private - sector competitor Celera Genomics of Rockville,
Human Genome Project and its private - sector competitor Celera Genomics of Rockville
Genome Project and its private - sector competitor Celera Genomics of Rockville, Md..
Over the course of a year, a committee led by Green and Leslie Biesecker, chief of the Genetic Disease Research Branch at the National
Human Genome Research Institute in Bethesda, Maryland, has been weighing how to handle «incidental findings» that turn up when a genome or exome is sequenced for some other medical r
Genome Research Institute
in Bethesda, Maryland, has been weighing how to handle «incidental findings» that turn up when a
genome or exome is sequenced for some other medical r
genome or exome is
sequenced for some other medical reason.
A new high - coverage DNA
sequencing method reconstructs the full
genome of Denisovans — relatives to both Neandertals and
humans — from genetic fragments
in a single finger bone
The move comes
in response to the announcement earlier this week of a new U.S. company, launched by
sequencing - machine manufacturer Perkin - Elmer and J. Craig Venter of The Institute for Genomic Research, that plans a brute - force approach to
sequencing the
human genome within 3 years (ScienceNOW, 12 May).
Since the publication of the
human genome sequence in 2001, scientists have found that the so - called junk DNA that lies between genes actually carries out many important functions.
«
Sequencing the
human genome, device miniaturization, and the advent of combination devices have shifted the focus from engineering to the life sciences
in the device industry,» adds Jules Mitchel, president of Target Health Inc.
in New York City, a company that conducts clinical trials for MD&D companies.
We obtain a
genome sequence from Kostenki 14
in European Russia dating to 38,700 to 36,200 years ago, one of the oldest fossils of Anatomically Modern
Humans from Europe.
«This was the ultimate
in identity theft,» says Venter, a biologist well known for his private - sector contribution to the
sequencing of the
human genome.
In the last decade, however, complete
genome -
sequence information and increasingly powerful bioinformatic tools have allowed us to generate and analyse draft interactome maps both for
humans and for other model organisms.
The expansive, sun - streaked laboratory sits above the university's renowned gene -
sequencing center, which proved a major player
in powering the
Human Genome Project.
Venter — who likes being compared to Galileo — led one of the teams that
sequenced the
human genome in the late 1990s.