Sentences with phrase «sequencing applications in»

Review: Next - generation sequencing applications in clinical bacteriology — Yair Motro — Biomolecular Detection and Quantification

Not exact matches

Sequence is a cloud - based ledger service for managing balances in financial and commerce applications like wallet apps, lending platforms, marketplaces, exchanges, and more.

Popular applications of theories about stages of faith can give the impression that there is a developmental sequence, through which most children and youths in the church can or do pass on the way to becoming adult Christians.

The policy — in the form of first Office Actions on a series of applications for patents on expressed sequence tags, ESTs — could greatly complicate basic gene therapy research by substantially allowing patents for small sequences of a gene that may later be used by the patent holder to corner ownership and uses of entire genes.

«We explored the opportunity of using sperm RNA elements as a predictor of human health, with applications at the fertility clinic that would go hand - in - hand with the new neonatal intensive care unit genome sequencing to better health outcomes,» said Dr. Krawetz, associate director of the C.S. Mott Center for Human Growth and Development.

Droplet - based microfluidics is a tool used in various applications like cell cultures, chemical synthesis and DNA sequencing.

As he was finishing his Ph.D., in 2010, the first full Neandertal genome sequence was released, and he realized his expertise might have an exciting application in ancient DNA.

The development of a new tool, CallHap, published in Applications in Plant Sciences, has made it cheaper and easier to sequence the chloroplast genomes of large numbers of plants and accurately track seed dispersal across landscapes.

It could also be relevant to clinical applications — it treats sequence uniqueness as a high priority and thus minimises the risk of potentially unwanted gene modifications, which must be avoided at all costs in gene therapy,» says Graf.

Just as the Human Genome Initiative in the 1990s sequenced human DNA for the subsequent identification and analysis of genes, so too will the Materials Genome Initiative sequence materials for identifying new properties for a variety of applications.

His research interests include the molecular underpinnings of cervical cancer (including developing genetic screens), the identification of the genetic determinants of quantitative traits in humans, and the application of massively parallel sequencing technology for understanding the genetics of complex disease.

Dr. Funari's research interests include developing new approaches for obtaining mycobiome profiles in human disease and the translation of next generation sequencing applications into the clinic and personalized medicine.

«There was a major gap for researchers using genomic DNA sequences to understand the evolution of species complexes,» says Ryan Folk, lead author of a study in a recent issue Applications in Plant Sciences.

The application of NGS to breast cancer research has enabled the development of cost - effective, multigene sequencing panels that have advanced our understanding of the disease and may in the future translate into better diagnosis and outcomes for patients.

And in spring 1995, when Avilion wanted to include the hTR sequence in her dissertation, the company tried to stop her out of concern that doing so would harm its patent application, Greider recalls.

The difficulties are well illustrated by last month's rejection of a patent application in the US, by the Institutes of Health, for DNA sequences without knowledge of the function of the gene.

Clearly, RNA sequencing and other techniques for RNA quantitation are in the early days of development and evaluation for clinical applications,» writes Howard Bauchner, M.D., Editor in Chief, JAMA, Chicago, in an accompanying editorial.

NHGRI's «flagship» sequencing program will expand beyond three huge centers and «sharpen its focus on medical applications,» said NHGRI Director Eric Green in a press call today.

Change ringing, in which a band of ringers plays long sequences of permutations on a set of peal bells, is a little - known but surprisingly rich and beautiful acoustical application of mathematics

As clinical sequencing becomes more common, pretest counseling will become more impractical and «lack of standardization and its application to patients of all circumstances might result in deeply varying levels of truly informed preference setting,» the group reasoned.

The entire procedure, including DNA extraction, sequencing, and marker analysis, is described in the November issue of Applications in Plant Sciences.

The system is inherently highly selective, but in practice it would likely be designed with multiple stages to deal with a variety of compounds in sequence, depending on the exact application, Su says.

«This will allow researchers to target an expanded range of sites in a variety of genomes, which will be useful for applications requiring highly precise targeting of DNA sequences.»

The company, Human Genome Sciences Inc. (HGS) in Rockville, Maryland, found the gene by sequencing human DNA and searching databases for possible genes; it didn't know there was a link to AIDS when it filed a patent application in 1995.

Moreover, the ability to easily program sequence - specific DNA targeting and cleavage by CRISPR - Cas components, as demonstrated for Cas9 and Cpf1, allows for the application of CRISPR - Cas components as highly effective tools for genetic engineering and gene regulation in a wide range of eukaryotes and prokaryotes.

Participants in the project blame the MRC's application to patent its sequences at the US Patent Office.

Dr. Mardis has research interests in the application of DNA sequencing to characterize cancer genomes and transcriptomes, and using these data to support therapeutic decision - making.

To synthesize the information and simplify the data - handling and processing workflow, Waters developed its Symphony software, a client / server application that allows the automation of one, or several, data - handling or processing functions in a sequence.

Each of the working groups is responsible for developing a proposal for a set of genomes to sequence that would advance knowledge in one of three important scientific areas: identifying areas in genetic research where the application of high - throughput sequencing resources would rapidly lead to significant medical advances; understanding of the human genome; and understanding the evolutionary biology of genomes.

The application of next - gen sequencing to RNA libraries (RNA - Seq), chromatin immunoprecipitates (CHiP - Seq), bisulfite - treated DNA, and regions of open chromatin (DNAse - Seq) makes it possible to interrogate many aspects of the genome in high - throughput fashion.

It also discusses the various new trends in the pharmacogenomics field, such as pharmacometabolomics - aided pharmacogenomics and the application of whole genome sequencing in pharmacogenomics.

Applications of next - generation sequencing, combined with powerful yeast genetics, now create tremendous opportunities to investigate both global contributions and specific roles of ncRNAs in genome regulation and phenotypic variation.

The Sequencing and Noncoding RNA Program is one of an MDA institution supported shared genomic service resources providing not only instrumentation but also expertise in applications of next generation sequencing and microarray services to invSequencing and Noncoding RNA Program is one of an MDA institution supported shared genomic service resources providing not only instrumentation but also expertise in applications of next generation sequencing and microarray services to invsequencing and microarray services to investigators

We concluded that an expanded Revive & Restore, in partnership with biotech organizations, will be able to offer services that include Genetic Insight (DNA sequencing and analysis), Biobanking (tissue collection and cell culturing), Advanced Reproductive Services (cloning and germ - line transmission), and Genome Engineering (CRISPR, gene - drive, etc.) Applications include restoring genetic diversity, augmenting adaptation to climate change, conferring resistance to disease, and extirpating harmful invasive species.

But through the application of genetic sequencing technology and analysis methods, SIGMA researchers were able to identify a single disease - causing mutation lying in a «blind spot» of modern sequencing techniques.

Speakers at the workshop will discuss progress in sequencing and with other technologies for biomolecular analysis, and their applications in research and clinical settings.

In order to apply for a sequencing scholarship, your application must be submitted by May 21, 2018 and your samples must be received by June 15, 2018.

By collaborating with NHS doctors, geneticists have shown that sequencing can have extremely important applications in healthcare today, halting an outbreak of a potentially deadly disease.»

Our products are designed for sequencing analysis of DNA in whole genome, whole exome, epigenetics, or amplicon applications.

Our work combines computational analysis of high - throughput sequencing data, population genetics, and experimental work.We focus in particular on studying genetic effects on the transcriptome traits, which has further applications in other traits at the cellular and individual level.

BETHESDA, Md., Thurs., Oct. 14, 2004 - The National Human Genome Research Institute (NHGRI), part of the National Institutes of Health (NIH), today announced it has awarded more than $ 38 million in grants to spur the development of innovative technologies designed to dramatically reduce the cost of DNA sequencing, a move aimed at broadening the applications of genomic information in medical research and health care.

The application of transgenesis and other genetic methods - in conjunction with total genome sequence and database information on gene expression patterns, morphological changes during development, and mutant phenotypes - should significantly enhance our ability to unravel the multilayered networks that control gene expression and differentiation.

Application of Sequence - Independent Amplification (SIA) for Identification of RNA Viruses in Bioenergy Crops, Bright Agindotan, Monday Ohonsi, Leslie Domier, Michael Gray, Carl Bradley, Journal of Virological Methods, 169 (1): pp. 119 - 128, October 2010.

Whether identifying rare subclones missed by standard bulk sequencing, or identifying co-mutation patterns in subclones, Tapestri Single - Cell DNA Panels can be applied across a wide number of applications, including hematologic malignancies, solid tumor profiling, and genome editing programs.

BGI is headquartered in Shenzhen, China and provides sequencing and bioinformatics services and systems for research, medical, agricultural, and environmental applications.

By leveraging the exponential improvements in the semiconductor industry (known as Moore's Law), the Ion Proton ™ Sequencing System provides an unprecedented level of scalability and flexibility to support a broad range of high throughput sequencing applications, ranging from human - scale genome to exome to transcriptome sSequencing System provides an unprecedented level of scalability and flexibility to support a broad range of high throughput sequencing applications, ranging from human - scale genome to exome to transcriptome ssequencing applications, ranging from human - scale genome to exome to transcriptome sequencingsequencing.

Dr. Shendure's research group in Seattle pioneered exome sequencing and its earliest applications to gene discovery for Mendelian disorders (e.g. Miller and Kabuki syndrome) and autism; cell - free DNA diagnostics for cancer and reproductive medicine; massively parallel reporter assays and saturation genome editing; whole organism lineage tracing; and massively parallel molecular profiling of single cells.

AGBT provides a forum for exchanging information about the latest advances in DNA sequencing technologies, experimental and analytical approaches for genomic studies, and their myriad applications.

As a recognized cornerstone for the genomics research community, AGBT provides an outstanding forum for exchanging information about the latest advances in DNA sequencing technologies, experimental and analytical approaches for genomic studies, and their myriad applications.

In addition, we support gene expression studies using Quant - seq (3» RNA - seq) and low input sequencing for most applications.