Sentences with phrase «sequencing efforts such»

Large - scale cancer sequencing efforts such as TCGA and ICGC have catalogued somatic mutations in a variety of common cancer types.

Not exact matches

Carr is leading one of the NASA sequencing efforts, and Johnson's technique could increase such a tool's usefulness.

As large - scale genome sequencing projects, such as the Human Genome Project, near completion, the research community's focus is shifting toward efforts to determine functional information about these sequenced genes.

Even as sequencing costs decline, such high - throughput efforts require pooling the DNA samples.

By better understanding the limitations of genome - wide sequencing, Vogelstein notes, researchers and policymakers might be better able to direct funding and efforts to areas, such as Alzheimer's disease, where a person's genetic profile might have a very real effect on their likelihood of getting the disease.

If such efforts succeed, says Robert Waterston, a geneticist who heads the genome sequencing center at Washington University in St. Louis, Missouri, the technique «could be the start of something impressive.»

It has launched projects such as a major effort to develop knock - out mice (ScienceNOW, 7 September 2006) and The Cancer Genome Atlas (Science, 16 December 2005, p. 1751), which, with the cancer institute, is sequencing mutations in human cancers.

She has contributed to widely varying fields — such as viral sequencing, information theory, rural disease surveillance, and education efforts in West Africa — to create comprehensive approaches for detecting, containing, and treating deadly infectious diseases.

Research Focus: I dedicate my time and effort to develop high - throughput sequencing technologies such as single cell transcriptomic, ChIP - Seq, ChIA - PET, and many more... The scientific rational is to understand better and with a different angle, the mechanisms of epigenetic regulation of gene expression in (rare) immune cells, pathologically relevant in many diseases such as asthma, SLE, tuberculosis...

As highlighted in the final print issue of Genome Technology, investigators leading clinical sequencing efforts have faced ethical dilemmas already, such as the return of genetic information to family members in the event that a patient dies.

Topics that will be explored include: • Cellular and developmental origins of pediatric cancer • Key findings of pan-cancer analysis efforts • Computational pipelines to analyze large - scale sequencing data • Opportunities for leveraging existing cancer genomics datasets • Strategies for integrative analysis of germline and somatic variants • Correlation of germline / somatic variation to clinical features such as tumor subtype.

A discombobulated effort with such distinctive sequences, it fails to maintain a full arc.

Tools to assist in the process are available (Devaney, O'Brien, Resnik, Keister, & Weissberg, 2006), and it can be helpful to compare with CASEL's scope and sequence chart of SEL activities across grade levels (Elias et al., 1997, Appendix A) and comprehensive frameworks that have resulted from such an assessment process (e.g., Anchorage School District, 2013) in orienting one's efforts.