Sentences with phrase «sequencing small fragments»

We have gone from sequencing small fragments of DNA to full mitochondrial genomes (17,000 base pairs of genetic code), and then in the last three years the field exploded into the realm of complete nuclear genomes.

Geneticists learned how to sequence small fragments of DNA and compare the versions of those fragments from different individuals.

Meanwhile, Memish says he had sent samples to the Wellcome Trust Sanger Institute in Hinxton, U.K., which sequenced the complete human virus and managed to sequence some small fragments of the camel virus.

Not exact matches

«We send DNA to be sequenced by the Joint Genome Institute, which is part of the U.S. Department of Energy, and they sequence it in lots of very small fragments.

Upon sequencing the DNA, they found that DNA fragments containing mutated genes — markers of tumors — were typically smaller than healthy versions of the gene from within the same patient.

To gain access to the gene - containing portion of the barley genome at high resolution, Close and his team identified and sequenced 15,622 BACs or bacterial artificial chromosomes — small fragments of the barley DNA linked to other DNA to constitute a circular molecule that can replicate and be propagated inside an E. coli bacterial cell, enabling researchers to produce copies of each BAC for DNA sequencing one small piece of the barley genome at a time.

Next - generation sequencing — the ability to sequence millions or billions of small fragments of DNA in parallel — has revolutionized the biological sciences, playing an essential role in everything from locating mutations that cause human disease to determining how a newly discovered animal fits into the tree of life.

Then they smashed the DNA into smaller fragments, sequenced 1.05 billion base pairs, and used computer models to reconstruct partial genomes of different species.

The sequencing technology works by first chopping the genome into single - stranded DNA fragments and combining them with snippets of known synthetic DNA so that they form small circles of about 400 bases.

Shallow shotgun metagenomics means instead of using the 16S rRNA as a marker gene, we fragment all the DNA in the sample, grind it up, sequence it in small pieces, and try to figure out what it is afterwards.

The difficulty in measuring such a small increment in chromosome 21 DNA concentration has recently been overcome with the use of massively parallel genomic sequencing.20 This technique can identify and quantify millions of DNA fragments in biological samples in a span of days.23 Three cohort studies have shown the feasibility of using the technique to identify fetuses with trisomy 21 by analysis of maternal plasma DNA.24 25 26 The sample numbers studied were small because, typically, only a few samples could be analysed in each sequencing run.

If the approaching spacecraft has to avoid plowing into smaller fragments, it would be a rather more graceful version of the famous asteroid - dodging sequence in Star Wars — fitting for a mission led by a jet jockey.

Small fragments of mitochondrial DNA were eventually sequenced, confirming the Asian Elephant's close kinship to the Woolly Mammoth — even closer than to African Elephants.

With longer (> 50 bp) fragment - end reads and / or paired - end libraries, it's possible to detect small insertion / deletion variants (indels) in next - gen sequencing data.

The quality thresholds used here produced levels and patterns of polymorphism for the 5,000 intronic fragments qualitatively similar to previous studies using a smaller dataset of intronic fragments and Sanger sequencing [21], [26](Table S6).

From the small fragments of DNA previously sequenced from the passenger pigeon, the closest living relatives of the passenger pigeon was identified as North American pigeons of the genus Patagioenas, including the west coast band - tailed pigeon.

Background: Oxford Nanopore Technologies Ltd (Oxford, UK) have recently commercialized MinION, a small single - molecule nanopore sequencer, that offers the possibility of sequencing long DNA fragments from small genomes in a matter of seconds.

The way we sequence DNA is by cutting them up into smaller, more manageable fragments, then piece them together like a giant puzzle.