Sentences with phrase «serous ovarian cancer cells»

«This study provides evidence that CA125 - negative high - grade serous ovarian cancer cells have stem properties and are inherently platinum resistant.

«We think that by isolating the CA125 - negative tumor cells we have uncovered this reservoir of carboplatin - resistant high - grade serous ovarian cancer cells.»

Not exact matches

A section of a tumor organoid grown from cells derived from a patient with high - grade serous ovarian cancer (left) and a mini-tumor treated with ReACp53, resulting in extensive cancer cell death.

This suggests that targeting the CA125 - negative cells may improve outcomes in these high - grade serous cancers, the most common subtype of ovarian cancer, said Memarzadeh, who also is a UCLA associate professor of obstetrics and gynecology and director of the G.O. Discovery Lab.

Ovarian cancer researchers have identified a protein biomarker expressed on the surface of tumour cells in high - grade serous ovarian cancer, the most common and lethal subtype of the dOvarian cancer researchers have identified a protein biomarker expressed on the surface of tumour cells in high - grade serous ovarian cancer, the most common and lethal subtype of the dovarian cancer, the most common and lethal subtype of the disease.

In lab experiments, the research team used cell lines derived from 40 patient tumour samples to identify that CD151 contributes to the survival of cells of high - grade serous ovarian cancer origin.

For the new study, described in the October 23rd issue of Nature Communications, scientists at the Johns Hopkins Kimmel Cancer Center and Dana Farber Cancer Institute in Boston collected tissue samples containing normal cells, ovarian cancers, metastases that had spread elsewhere, and small cancers found in the fallopian tubes, which included single cell layers of cancer called «p53 signatures» and serous tubal intraepithelial carcinoma, or STIC leCancer Center and Dana Farber Cancer Institute in Boston collected tissue samples containing normal cells, ovarian cancers, metastases that had spread elsewhere, and small cancers found in the fallopian tubes, which included single cell layers of cancer called «p53 signatures» and serous tubal intraepithelial carcinoma, or STIC leCancer Institute in Boston collected tissue samples containing normal cells, ovarian cancers, metastases that had spread elsewhere, and small cancers found in the fallopian tubes, which included single cell layers of cancer called «p53 signatures» and serous tubal intraepithelial carcinoma, or STIC lecancer called «p53 signatures» and serous tubal intraepithelial carcinoma, or STIC lesions.

To date, the TCGA Research Network has generated data and published analyses on glioblastoma multiforme, ovarian serous adenocarcinoma, colorectal adenocarcinoma, lung squamous cell carcinoma and invasive breast cancer.

The book introduces the incessant menstruation hypothesis, which may allow physicians to better understand and explain to patients why many serous ovarian cancers may actually be originating from the fimbriated end of the fallopian tube and why endometrioid and clear cell cancers may arise in association with endometriosis.

a. Mechanism - guided therapeutic strategies for genetic alterations that affect the SWI / SNF chromatin remodeling complex in epithelial ovarian cancer (such as ARID1A mutation in clear cell and endometrioid subtypes of ovarian cancer, and CARM1 amplification / overexpression in high - grade serous ovarian cancer).