But overdoses of iron - containing (ferrous sulfate) vitamin / mineral supplements, sudden liver damage that releases stored iron, excessive blood loss, hemolytic anemias and bone marrow disorders have all been associated with high
serum iron levels.
Furthermore, C326S ferroportin mutant mice with a disrupted hepcidin / ferroportin regulatory circuitry respond to injection of the TLR2 / 6 ligands FSL1 or PAM3CSK4 by ferroportin down regulation and a reduction of
serum iron levels.
Not exact matches
All patients had
iron deficiency, defined as a
serum ferritin
level of less than 100 ng / mL, or between 100 and 300 ng / mL if transferrin saturation [TSAT] was less than 20 %.
Since blood
levels of retinol - binding protein change with pregnancy, the
serum retinol test can yield inaccurate results.22 Be aware that routine
iron supplementation is not advisable during pregnancy, since an increased
iron intake in women with an already adequate
iron status may have adverse effects.
If you suspect low or high
levels of
iron, have your
levels checked with a
serum ferritin test before doing anything.
Serum ferritin
levels — excess
iron can damage the inner lining of the blood vessels creating massive amounts of free radicals.
Therefore, a plant - based diet, which may lead to lower
serum ferritin
levels, may not be a disadvantage when
iron intake is sufficient and diet replenishes loses.
http://www.ncbi.nlm.nih.gov/pubmed/15854860 «This report describes a patient with
iron deficiency in bone marrow examination and
iron - responsive restless legs syndrome (RLS), in whom
serum ferritin
levels were well above the conventional cutoff for considering
iron deficiency» (full report: http://www.idpas.org/pdf/4176.pdf)