The 1500 transcription factors (TFs) within the human genome perform a key role in determining
the set of active genes within a specific cell, as well as the magnitude of activity.
The new study examined the entire
set of active genes, or the transcriptome, of 24 conifers and other seed plants and three distantly related plants.
Not exact matches
To generate a rich source
of potential vaccine and drug target candidates, the team identified a
set of genes that are more
active in certain stages
of the parasite life cycle and within the parasite's gut.
By using this tool to analyze their data the scientists were able to catalogue
active alleles in a comprehensive
set of mouse tissues, or the mouse «Allelome,» and gain an insight into how this differential
gene activity is regulated.
What makes a horse different from a tiger, a mouse and a walrus is the
set of regulatory switches in the DNA that dictate where, when and for how long those
genes are
active.
A major effort in the lab is to elucidate the
active components
of this process and to apply transcriptional
gene silencing in a therapeutic
setting.
Although both cell types come from cells known as myeloid progenitors, each type relies on its own
set of functionally
active genes to carry out its particular role in fighting infection.
Human Biology Division discovery reveals that the CTCF protein that forms protective boundaries between inactive,
active sets of genes; may shed light on how some cancers develop
Each cell type relies on its own
set of functionally
active genes to carry out its particular role in fighting infection.