Sentences with phrase «set of organoids»
Researchers exposed another set of organoids derived from the same Alzheimer's patients to experimental compounds known to prevent the secretion or accumulation of amyloid, and they discovered that the plaques didn't form.
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To turn these cellular LEGOs into arrays of organoids that can be used for research, Gartner's team lays down the cells in layers, with multiple sets of cells designed to stick to particular partners.
«This work provides a proof of principle for using stem cell - derived human intestinal organoids in a therapeutic setting.»
Next - generation «designer matrices» such as hybrid polyethylene glycol hydrogels or microengineered collagen scaffolds, combined with a well - defined set of laminins, may better fulfill the niche requirements of organoids and may be customized for a specific type of tissue / organoid (2,6).
The other one, the finding by the Clevers group in Utrecht that adult Lgr5 + stem cells from the intestine, grown 3D in the presence of basement membrane matrix and a defined set of niche factors, can develop into ever - expanding, genome - stable 3D organoids that resemble the structure and function of the original intestinal epithelium (13 - 16).