Thirty companies and academic groups will receive the same
set of tumor samples from individual patients and will try to predict the best neoantigens.
Not exact matches
The Ogretmen laboratory screened previously reported microarray data
sets of several human
tumor tissues (metastatic head and neck squamous cell carcinoma, melanoma, and renal cell carcinoma) and showed that, in these
samples, only the levels
of CerS4 were significantly decreased.
The role
of rebiopsy and repeat analysis in the
setting of post-treatment relapse, along with testing
of blood
samples for mutations in circulating
tumor cells, cell free
tumor DNA, or exosomes will be considered.
An additional
set of 18 prostate cancer tissue
samples was analyzed by qPCR and five lncRNAs were found to be significantly higher in prostate
tumor tissues compared with matched normal tissues.
The initial version
of CRI iAtlas is based on an analysis performed by The Cancer Genome Atlas (TCGA) Research Network on the TCGA data
set comprising over 10,000
tumor samples and 33
tumor samples (Thorsson et al..
In the first
set of experiments, the Johns Hopkins scientists sequenced nearly all protein - encoding genes in 10
of the 68
samples of pancreatic neuroendocrine
tumors and compared these sequences with normal DNA from each patient to identify
tumor - specific changes or mutations.