Once inside, they can disrupt
several cellular targets, including DNA, RNA, and proteins.
Taken together with the fact that
several cellular target are addressed, this could provide a novel approach for tuberculosis treatment.
Not exact matches
The lab focuses on clarifying the mechanisms of brain plasticity, gene expression, and responses of
cellular elements to different psychotropic drugs, and have identified
several novel brain sites and pathways that constitute attractive
targets for new drug development.
He has made
several important contributions in this area including identifying a new strain of CHIKV virus, identification of host
cellular targets of HIV accessory genes, new novel DNA vaccine approaches for HIV, CHIKV, RSV, Dengue, MERS and Zika among others.
Therefore, the identification of
cellular and molecular mechanisms underlying neuron - astrocyte communication will help to a better understanding of the mechanisms of brain phsyiology as well as to appropriately identify
cellular targets to direct therapeutic approaches for the future treatment of
several brain diseases.