Aneuploidy is known to be deleterious and underlies
several common human diseases, including cancer and genetic disorders such as trisomy 21 in Down's syndrome.
Not exact matches
Brief exposure in infancy to
several industrial chemicals that are
common in the
human environment, particularly bisphenol A (BPA), caused fatty liver
disease in adulthood, the researchers found in rats.
«Although we first became aware of prions because they cause
several bizarre neurological
diseases, the discovery that something so awesomely similar happens in organisms as different as
humans and yeast makes us suspect that there is a fundamental,
common biochemical process at work here,» said study director Susan Lindquist, PhD, professor of molecular genetics and cell biology and an investigator in the Howard Hughes Medical Institute at the University of Chicago.
In addition, recent genome - wide association studies have identified
several hundred
common genetic variants — inherited changes in the DNA sequence of the
human genome — that play a role in an individual's susceptibility to complex
human illnesses such as heart
disease, mental illnesses, cancer and diabetes.
Several common human nematode parasites cause intestinal and subcutaneous
disease including the ascarids, filarias, ancylostomids (hookworms), Enterobius (pinworms / threadworms) and Trichuris (whipworms).