Sentences with phrase «several gene families»

Genome comparison revealed that the great expansion of several gene families in the deep - sea mussel may be related to its adaptation to the deep sea.

Snake venoms are complex protein mixtures encoded by several gene families and these proteins function synergistically to cause rapid paralysis or death in prey.

Not exact matches

Genes and words have several similarities, and language evolution has conventionally been mapped using a «family tree» format.

Interestingly, the let - 7 family of micro RNA affects several key genes that regulate glucose metabolism, called the PI3 / AKT / insulin pathway.»

Sex determining genes exist in several different variants, but close family members are likely to share the same variants.

A paper they published in the journal Science several months ago has gotten a lot of attention, because after detecting a suspect allele in Finnish families with asthma, the researchers found the same gene in families with asthma in Quebec.

The analysis suggested that a protein produced by a gene called Olig2, which is only expressed in the neural progenitors that create motor neurons, promotes motor neuron formation by interfering with the activity of several members of another gene family — the Hes genes.

Using methods for analyzing gene expression in mice, they identified several members of the «BMP» family of proteins from among more than 20,000 possible candidates.

«When we found this causal gene and were able to reveal it to the family, it was an emotional moment,» said Natasha Frank, MD, the clinical geneticist at BWH who treated several members of the family.

The Cancer Dependency Map team's RNAi screening experiments turned up genes corresponding to several families of proteins.

A team of French and American scientists at several institutes pinpointed mutations in the retinal guanylate cyclase (RETGC) gene in eight families in which the disease has struck.

Although it shows no sign of the whole - genome triplication identified in Solanaceae species such as tomato, the genome includes several species - specific gene family expansions, among them N - methyltransferases (NMTs) involved in caffeine production, defense - related genes, and alkaloid and flavonoid enzymes involved in secondary compound synthesis.

In addition, researchers found that the gene families related to whale's body hair and sensory receptors were contracted, such as Keratin - related gene families associated with hair formation, several Hox genes that play an important role in the body plan and embryonic development.

To nail down these evasive genes, teams led by human geneticist Jonathan Haines of Vanderbilt University in Nashville, Tennessee, and neurologist Jan Hillert of the Karolinska Institute in Stockholm, Sweden, compared several thousand MS patients from the United States and Europe with their family members and healthy controls.

The combination of the University of Utah's genomics expertise and local families» detailed genealogical data has been key to discovering several genes responsible for certain forms of breast and colon cancer.

This approach, which relies on a few large families, can produce misleading results for a disorder such as ADHD which may involve several genes, unlike single - gene disorders such as cystic fibrosis or Huntington's disease.

The researchers found that patients from MODY3 families had one of several different mutations in the gene for hepatocyte nuclear factor 1 alpha (HNF -1-alpha) but healthy subjects had normal copies of the gene.

Several types of chemical modifications of the five major histone protein families give rise to a complex «histone code» that signals the transcriptional machinery to turn genes on or off.

They identified several causal variations in CCDC115 gene: a homozygous missense mutation, c. 92T > C (p.Leu31Ser) and this one was also compound heterozygous in combination with a heterozygous deletion of CCDC115 (in one family) and a homozygous missense mutation, c. 31G > T (p.Asp11Tyr).

Recently, some other cytokines (such as tumor necrosis factor) or chemical drugs were also found to up - regulate several IFN - inducible gene family members (including RIG - G) through production of type I IFNs (37, 38), further indicating that the induction of RIG - G by ATRA in NB4 cells was tightly related with an IFNα autocrine pathway.

Most of these are shared between the two species, but some appear to be expanding or contracting, and there seem to be as many as several hundred novel C. briggsae gene families.

And yet, even after you sequence the exomes of several family members (affected and unaffected) the causal variant or gene remains elusive.

Several GenoMEL groups looked at genes in over a hundred families from the UK, the Netherlands and Australia that do not carry any known mutations.