Primarily, it turns on
several genes for proteins that help the cells adapt to the lack of oxygen.
Not exact matches
Tsai's group manipulated the
gene for the
protein p25, which has been implicated in
several neurodegenerative diseases, so that it could be easily switched on and off.
Researchers from
several institutions, including, UCLA, Boston University, Stanford University and the Institute
for Aging Research at Hebrew SeniorLife, analyzed blood samples from nearly 10,000 people to find that genetic markers in the
gene responsible
for keeping telomeres (tips of chromosomes) youthfully longer, did not translate into a younger biologic age as measured by changes in
proteins coating the DNA.
They studied KAP1, a
gene that codes
for an essential
protein associated with
several fundamental processes in neurodevelopment.
The KAP1
protein acts as a regulator
for several other
genes which allow the brain to grow healthily and develop
several types of brain cell.
Several of the viruses also release the
gene for granulocyte - macrophage colony - stimulating factor (GM - CSF) an immune system
protein.
Further investigation, says Resar, showed that these unusual properties arise from the ability of HMGA1 to turn on
several genes involved in the Wnt pathway, a network of
proteins necessary
for embryonic development and stem cell activity.
The ADGRE2
gene provides instructions
for production of ADGRE2
protein, which is present on the surface of
several types of immune cells, including mast cells.
Several previously reported
genes from simpler organisms code
for proteins that oscillate in abundance.
Researchers have known
for several years that when fruit fly larvae metamorphose into adults, a
gene called fringe produces a
protein that tells certain cells to become the wing margin, the leading edge of a developing wing.
EB results from mutations to any of
several genes that encode
proteins crucial
for anchoring the outer layer of skin, the epidermis, to the tissue below.
Using methods
for analyzing
gene expression in mice, they identified
several members of the «BMP» family of
proteins from among more than 20,000 possible candidates.
The team also discovered
genes for several of the
proteins that make up the molecular scissors, or spliceosomes, that remove introns as the
gene is translated into a
protein.
The other finding was of a variant near
genes for several so - called semaphorins,
proteins that guide developing nerve cells as they grow toward their final targets.
Negotiations with the U.S. company that holds the license
for commercialization of the vaccine — which contains a
gene for the Ebola surface
protein stitched into a livestock pathogen known as vesicular stomatitis virus (VSV)-- have needlessly delayed the start of the trial, Becker and
several other scientists tell Science.
But after
several questions about potential outcomes of such early research, Niakan did «wildly speculate» that, if certain
genes are found to be particularly important
for development, one eventual approach might be to check during IVF whether eggs were making the
proteins encoded by those
genes, and if not, then add them to culture media.
Jeffrey Hall and Michael Rosbash of Brandeis University in Waltham, Massachusetts, and Michael Young of The Rockefeller University in New York City share the prize equally
for their work on how
several genes work together to control the basic circadian clock, encoding
proteins that build up during the night and are broken down during the day.
In partnership with
several international programs, the initial five - year phase of KOMP will reach its goal of creating knockout mouse embryonic stem cell lines
for each of the approximately 21,000
protein - coding
genes in the mouse genome this year.
But Yang targeted
several genes that code
for the
protein that causes mushrooms to turn brown as they age or get bruised.
Gene ontology analysis of the
genes affected across
several tissues (Supplementary Fig. 8) shows enrichment
for genes in the extracellular region and
genes involved in nucleosome and chromatin assembly and in
protein — DNA complexes.
Despite evidence
for divergence at
several loci, certain 1a characteristics were preserved including the length of the alternative reading frame / F
protein (ARF / F)
gene, and a subtype 1a - specific phosphorylation site in NS5A (S349).
Over the last
several years, sequencing patients»
protein - coding
genes — known as whole - exome sequencing — has facilitated molecular diagnosis and as served as a research tool
for discovering the fundamental genetic bases
for over 100 Mendelian diseases.
In another clinical study on healthy subjects done at Ohio State University Wexner Medical Center (OSUWMC), PrimaVie was found to upregulate the
genes responsible
for the synthesis of collagen and
several other related
proteins — a total of 17.
Hundreds of studies have indicated that practicing this diet
for several years can help fight a host of potential causes of inflammation, help maintain a healthy
protein turnover rate — a process critical to slowing the aging process — and it even activates an incredibly powerful anti-aging
gene.