The test tube finding, reported in the current Cell, could help explain the formation of prions — the tangled proteins that are implicated in mad cow disease and
several human brain disorders — and eventually may lead to a way to smooth out these rogue proteins.
Not exact matches
A recent study published in Annals of Neurology reports that healthy
human tissue grafted to the
brains of patients with Huntington's disease in the hopes of treating the neurological
disorder also developed signs of the illness,
several years after the graft.
In the new study, the researchers discovered that during the second trimester of
human brain development, oRG cells express genes related to a fundamental signaling pathway called mTOR, defects in which have previously been implicated in autism and
several other psychiatric
disorders.
The presence of
several mutations in four important genes for the
brain's synapses can be associated to Obsessive Compulsive
Disorder in
humans.