Not exact matches
Through these effects, the PERY peptide reduced the proliferation of
several (but not all)
cancer cell lines in culture and inhibited the growth of a
human breast
cancer xenograft in mice.
Slashing the amount of HSF1 in
several lines of
human cancer cells diminished growth and survival.
The authors studied a standard panel of 60 established
human tumor
cell lines representing nine different
human cancers, as well as
several specimens of
human primary ovarian
cancer.
I wanted to inactivate the gene BRAF (a kinase implicated in
several human cancers) in A549
cells (a
human lung
cancer cell line), armed only with viruses obtained through Addgene's viral service and the methods sections of scientific articles (gasp).
(a kinase implicated in
several human cancers) in A549
cells (a
human lung
cancer cell line), armed only with viruses obtained through Addgene's viral service and the methods sections of scientific articles (gasp).
Important features of XMRV biology include (1) tropism for a variety of
cell lines, including prostate
cancer DU145 and LNCaP
cells [27], [43], [48], and
human neural
cell types [57], (2) adaptations that promote growth in prostate epithelium and
human - derived prostate
cancer cell lines including an androgen response element in the promoter region [58] and downregulation of APOBEC3G [59], and (3) cellular effects with potential oncogenic properties including increased tumor aggressiveness mediated by downregulation of p27 [60] and differential regulation of
several microRNAs [61].