Sentences with phrase «several human cancers»

STAT5 belongs to a family of transcription factors that regulate cytokine - induced gene expression and is constitutively activated in several human cancers including breast cancer, where it promotes the expression of genes encoding cell survival factors (44).

Knocking out or blocking the activity of Nrp1 on regulatory T cells in mouse models of several human cancers, including the deadly skin cancer melanoma, led to reduced, delayed or complete elimination of the tumors.

The extract was found to have cytotoxicity against several human cancer cell lines, while promoting apoptosis and cell cycle arrest.

I wanted to inactivate the gene BRAF (a kinase implicated in several human cancers) in A549 cells (a human lung cancer cell line), armed only with viruses obtained through Addgene's viral service and the methods sections of scientific articles (gasp).

POSTN is a secreted protein that is incorporated in the extracellular matrix and has been associated with metastasis in several human cancers (Conway et al., 2014).

(a kinase implicated in several human cancers) in A549 cells (a human lung cancer cell line), armed only with viruses obtained through Addgene's viral service and the methods sections of scientific articles (gasp).

Inactivation of ABL kinases inhibited the expression of the TAZ target gene AXL, which shows increased expression in several human cancers and correlates with poor prognosis, increased invasiveness and metastasis, and enhanced drug resistance (53, 54).

Persistent Organic Pollutants (POPs) are persistent and ubiquitous around the world; they are linked to several human cancers.