In a recent speech he laid down
several markers of change he wanted to see happen in the Courts system.
Closely monitoring
several markers of cell damage (including creatine kinase, lactate dehydrogenase, prostaglandin - E and tumor necrosis factor - alpha) in their sample of 18 male athletes (who used 20 grams of creatine monohydrate per day for five days, mixed with 60 grams of maltodextrine), the researchers found levels of these markers were reduced after the race, compared to 16 control subjects who took only the maltodextrine.
After 12 weeks, they had seen improvements in
several markers of brain function (25).
In one set of experiments, when the scientists boosted insulin resistance by giving mice a compound that cuts insulin signaling, they saw increased expression of
several markers of aging in beta cells.
The scientists identified
several markers of aging beta cells, including one protein called IGF1R that is an important player in cell survival.
«The new method has allowed us to measure
several markers of diet and nutrient status at the same time in a large number of people, which we believe is the first time this has been done,» he says.
The research, published in PLOS ONE, found that
several markers of insulin resistance were increased following sustained exposure (6 - 8 weeks) to hypoxia at high altitude and that this change was related to increased blood levels of markers of inflammation and oxidative stress.
Not exact matches
In my case,
several nurses noted I had classic physiological
markers for insufficient glandular tissue plus a history
of infertility, but specifically noted that they chose not to tell me.
Upon narrowing the study's focus to the three smallest and least studied U.S. racial groups, Pacific Islander, multiracial, and American Indian adolescents had higher prevalence for using
several illicit substances as well as every
marker of suicidality compared to non-Hispanic white adolescents.
In that study, the UChicago researchers matched genetic
markers of the «input» and «output» neurons
of the mammalian neocortex with genes expressed in
several bird DVR nuclei.
Researchers from
several institutions, including, UCLA, Boston University, Stanford University and the Institute for Aging Research at Hebrew SeniorLife, analyzed blood samples from nearly 10,000 people to find that genetic
markers in the gene responsible for keeping telomeres (tips
of chromosomes) youthfully longer, did not translate into a younger biologic age as measured by changes in proteins coating the DNA.
These
markers do not make any proteins, but they contain the names
of 46 scientists on the project and
several quotations written out in a secret code.
Several researchers, however, are tracking chemical
markers in the blood and in the breath with the goal
of creating screening tools that could someday not just find cancer but also indicate how dangerous it is likely to be.
Despite this, the extensive breadth
of the new study allowed the researchers to identify
several genetic
markers underlying the fruit size increases, which is great news for breeders who might want to further increase the apple's girth.
After watching those mice thrive for
several months, Lagasse repeated the experiment using fluorescent
markers to trace the path
of the liver cells.
«Thanks to this innovative approach that connects
several layers
of information, we were able to identify a urinary
marker that can easily detect the presence
of a case
of diabetes,» said Johan Auwerx.
«By analyzing the blood
of children
of controls and comparing it to children
of bipolar patients, we identified
several genes or
markers that can explain the increased risk.»
Several studies have used cell - surface
markers — proteins found on the outer membranes
of tumor cells — to identify glioblastoma stem cells; but the specific
markers used have been controversial and can not reflect molecular processes going on within tumor cells.
Researchers at Stanford University School
of Medicine have identified
several new biological
markers to measure the progression
of the inherited neurodegenerative disorder Huntington's disease (HD).
The cells are tiny — a few could fit on the head
of a pin — so a single biodrone could carry
several, enabling it to measure multiple atmospheric
markers simultaneously.
These included wakeup glucose levels; levels
of the essential minerals calcium, iron, and magnesium; fat and cholesterol levels; kidney and liver enzymes; and
several markers for inflammation and tissue damage.
Each
of these magnetic
markers is designed to target specific sites within biomolecules and thus enables
several approaches for the structural analysis
of different biomolecules.
In a statement put on the Web this morning, NIH reported that all 64 lines «show characteristics
of stem cell morphology» and have undergone
several population doublings, and most
of them have demonstrated all the protein
markers «known to be associated with human embryonic stem cells.»
Kisspeptins circulating in the blood increase dramatically during normal human pregnancy, to
several thousand times non-pregnancy levels, which makes them a novel predictive
marker for assessing the risk
of later complications.
A type
of antifungal antibody, called ASCA, is widely used as a diagnostic
marker since it is highly elevated in the blood
of patients with
several chronic diseases including Crohn's.
A section
of a head and neck tumor — red and green
markers show the proliferation
of cancer stem cells — that formed when one
of several newly characterized genes, Myh9, was suppressed.
Instead
of focusing on just a few pre-defined
markers, metabolomics analysis allows for the determination
of the study participants» metabolic profile, i.e. the concentrations
of several metabolites.
He's identified
several families with a strong hereditary pattern
of the disease and has begun searching for common genetic
markers.
Numerous stem rust resistance (Sr) genes are known and in recent years
several of these have been cloned and used to develop so - called «perfect»
markers to allow more rapid and accurate breeding.
(6) Moreover, subcutaneous adipose
of prematurely - aged transgenic mice exhibited high levels
of staining for the senescence
marker senescence - associated - β - galactosidase (SAβ - gal) and expressed high levels
of several established
markers of senescence, including p21, p19, interleukin - 6, (insulin - like growth factor binding protein - 2 (Igfbp2), and Pai - 1; primary BubR1H / H; INK - ATTAC mouse embryonic fibroblasts forced artificially into senescence by oncogenic Ras or serial passage exhibited a subpopulation that was both GFP + and stained positively SAβ - gal.
We therefore used
several approaches and different nuclear
markers to infer the phylogenetic relationships and to estimate the amount
of gene flow between ancient and modern horses.
SapTrap includes a prebuilt donor plasmid library containing
several types
of fluorescent (EGFP, tagRFP, mCherry) and nonfluorescent (Halo, SNAP) tags, a selectable
marker -LRB-
SapTrap includes a prebuilt donor plasmid library containing
several types
of fluorescent (EGFP, tagRFP, mCherry) and nonfluorescent (Halo, SNAP) tags, a selectable
marker (floxed Cbr - unc - 119) for easy screening
of the insertion event, and a variety
of connector modules (linker sequences between the tag and homology arms).
Several postmortem studies report the presence
of inflammatory
markers in the brains
of depressed or mood - disordered patients.
The researchers followed up to identify
markers of aging in these cells, using
several mouse models — one with impaired glucose tolerance (a contributor to type 2 diabetes progression) and another that shows
markers of rapid aging.
Six Xa genes have been tagged with molecular
markers and used to help identify new resistant lines, resulting in the release
of resistant varieties in
several countries.
Of note, mouse neural stem cells (NSCs) were reprogrammed using only one (Oct4) or two factors (Oct4 and Klf4), due to the endogenously high expression of pluripotent genes, such as Sox2 and c - Myc, as well as several intermediate reprogramming markers [14], [17], [18
Of note, mouse neural stem cells (NSCs) were reprogrammed using only one (Oct4) or two factors (Oct4 and Klf4), due to the endogenously high expression
of pluripotent genes, such as Sox2 and c - Myc, as well as several intermediate reprogramming markers [14], [17], [18
of pluripotent genes, such as Sox2 and c - Myc, as well as
several intermediate reprogramming
markers [14], [17], [18].
A combination
of several germ cell
markers will thus be necessary to detect germ cell differentiation from ES cells.
There are currently no disease - modifying treatments that have been shown to slow the progression or delay the onset
of HD in humans; however,
several compounds have demonstrated promise in animal models
of HD.1 Robust and sensitive
markers of disease progression are required to assess their efficacy in humans.
With the RNAscope ® duplex assay we demonstrated localization
of PD - L1 and
several immune
markers in lung cancers.
«I've woken up from the sound
of my wheels on road
markers on
several occasions,» says the former applications engineer, a dad who used to endure a 55 - mile commute.
Several of my inflammatory
markers were higher than I wanted them to be, meaning I was moving in the wrong direction on the autoimmune spectrum.
A study
of young male athletes found that 2 weeks
of supplementing with CLA improved
several inflammatory
markers and reduced inflammation.
I can't say for certain that after undergoing advanced lab studies (LDL particle number and size,
markers of inflammation, tests for genetics like homocysteine, MTHFR and clotting, lipoprotein a, fibrinogen, and ferritin levels) that I would have found one or
several defects to treat in Felicia's husband, but it is likely.
Specifically, they found that berberine significantly inhibited amyloid beta - stimulated production
of several inflammation
markers, including interleukin - 6 and monocyte chemotactic protein - 1.
For the study, 10 individuals ran and walked at different speeds on a uniquely designed treadmill;
several cameras captured their gait with monitoring reflective
markers placed on different parts
of the individuals» lower limbs as the treadmill collected data from the applied force.
Surprisingly, the researchers did not find increased levels
of Alzheimer's
markers when they looked specifically at people with obstructive sleep apnea, a breathing disorder that's a major disruptor
of sleep and a risk factor for
several other chronic diseases.
Several years ago investigators tracked the biotin status
of thirteen pregnant women through the course
of their pregnancies, measuring a
marker of deficiency in their urine.
Of these, several have reported post-treatment reductions in total cholesterol 12, 53, triglyceride 12, 53 and increases in high density lipoprotein (HDL) cholesterol.20 In studies using normotensive rats, three to six months of IER has been observed to lower blood pressure 16 - 19 and heart rate 16, 17, 19, with the magnitude of the change comparable to CER (40 % ER / day) rats.19 In accordance with these findings areimprovements in aortic endothelium - dependent and heart rate variability (a marker of sympatho - vagal balance) in IER - fed rats.
Of these,
several have reported post-treatment reductions in total cholesterol 12, 53, triglyceride 12, 53 and increases in high density lipoprotein (HDL) cholesterol.20 In studies using normotensive rats, three to six months
of IER has been observed to lower blood pressure 16 - 19 and heart rate 16, 17, 19, with the magnitude of the change comparable to CER (40 % ER / day) rats.19 In accordance with these findings areimprovements in aortic endothelium - dependent and heart rate variability (a marker of sympatho - vagal balance) in IER - fed rats.
of IER has been observed to lower blood pressure 16 - 19 and heart rate 16, 17, 19, with the magnitude
of the change comparable to CER (40 % ER / day) rats.19 In accordance with these findings areimprovements in aortic endothelium - dependent and heart rate variability (a marker of sympatho - vagal balance) in IER - fed rats.
of the change comparable to CER (40 % ER / day) rats.19 In accordance with these findings areimprovements in aortic endothelium - dependent and heart rate variability (a
marker of sympatho - vagal balance) in IER - fed rats.
of sympatho - vagal balance) in IER - fed rats.72
Stress resistance has not been assessed however and so the biological relevance
of this finding is currently unknown.32
Several IER trials (75 - 85 % ER on restricted days) in overweight / obese populations have reported reductions in various
markers of oxidative stress 37, 41, which in one study was accompanied by a complementary increase in the anti-oxidant uric acid.37 In a direct comparison
of IER (75 % ER for two days / week) and CER, both ER strategies displayed equal efficacy in reducing levels
of fast - acting advanced oxidation protein products (AOPP) after six months, which displayed a tendency to occur earlier (i.e. at three months) in the IER group.41 Levels
of slow - acting (i.e. long term) AOPP tended to decrease in the IER group and increase in the CER group which the authors proposed may have resulted from IER - induced activation
of autophagy, a key homeostatic cellular process in which dysfunctional or unnecessary cellular proteins are degraded and recycled.41 On the other hand, a follow - up study using similar IER / CER protocols demonstrated comparable reductions in AOPP in both groups after three months.48 Summary and Future Research Directions