Sentences with phrase «several mutations»

The only way the virus could become resistant to this approach would be to develop several mutations at the same time, which is highly unlikely to happen.

A team led by co-senior author David Fitzpatrick, BMBS, at the University of Edinburgh did not find any effects of SMCHD1 mutations in mice, and Talkowski notes that this may reflect the involvement of several mutations in arhinia — similar to the way SMCHD1 mutations contribute to FSHD2 — and that many factors can alter how the conditions are manifested.

But a comparison of its DNA to that of another human has revealed several mutations in genes involved in bone disorders — and confirmed once and for all that this being is definitely from our world.

She uses the metaphor of disease as the mediation on colonialism and post-colonialism interpreted through poetically drawing the act of a virus entering the body in question and rendering the body as a host, in which several mutations occur for the survival of the virus.

She uses the metaphor of disease as a mediation on colonialism and postcolonialism interpreted through poetically drawing the act of a virus entering the body in question and rendering the body as a host, in which several mutations occur for the survival of the virus.

It was carried directly from Europe by such leaders as Count Zinzendorf, Henry M. Muhlenberg, and Theodore Freylinghuysen, and — crossed with English evangelicalism or Methodist — it blossomed with several mutations and sports in the hothouse atmosphere of the Great Awakenings.

Their preliminary analysis revealed several mutations known as single nucleotide polymorphisms (SNPs) in the ALR gene, many of which haven't been identified before.

Fortunately, the African strain seen in Brazil does not appear to have developed several mutations detected in Southeast Asia.

They found several mutations of particular interest that add a new sugar molecule to the hemagglutinin, thus creating a novel «N - linked glycan» site.

By comparing the whole genome sequence of the lab - cultured resistant strain with a sibling strain that had not been exposed to the drug, they were able to identify several mutations of interest in a number of genes.

These findings may explain how several mutations reported in human cancer can compromise the «off switch» of ALC1.

Any of several mutations and aberrations can push the pathway into a hyperactivated state, pressing a cell to grow and divide more than its environment calls for.

In a disease state, several mutations in TDP - 43 have been identified as a cause of some hereditary and sporadic ALS and FTD cases.

Several mutations were found in genes coding the machinery that makes mitochondrial proteins, and so would probably hinder mitochondria's ability to make the chemical fuel called ATP, which is used by normal cells.

The rationale is that several mutations are necessary to change the number of trunk vertebrae, with single mutations leading to irregularly shaped transitional lumbosacral vertebrae that are incompletely and asymmetrically fused to the sacrum.

He alleges that, because many functional adaptations require multiple changes in proteins, two or more mutations must occur together at the same time in the same gene and only rarely can several mutations «sequentially add to each other to improve an organism's chances of survival.»

We imputed these variants into 104,220 individuals down to a minor allele frequency of 0.1 % and found a recessive frameshift mutation in MYL4 that causes early - onset atrial fibrillation, several mutations in ABCB4 that increase risk of liver diseases and an intronic variant in GNAS associating with increased thyroid - stimulating hormone levels when maternally inherited.

Several mutations in BRCA1, for example, have been shown to alter that gene's splicing and increase cancer risk.