Sentences with phrase «several tumor types»

PKC is also a well - established anti-apoptotic factor expressed in several tumor types.9

Anticancer activities of several anthelminthics attracted considerable interest, especially their capacity to target signal transduction pathways of CSCs / TICs of several tumor types.

Checkpoint inhibitors such as ipilimumab, nivolumab and pembrolizumab have had a dramatic impact on treatment of several tumor types, including melanoma, lung cancer, head and neck cancers and others.

Not exact matches

But there can be several different types of cell in a uterine carcinosarcoma tumor, including ones that are not usually found in the uterus.

Consider Cushing's disease, in which any of several types of tumors produce astronomically high glucocorticoid levels.

Liver Steroids can form blood - filled cavities and several types of benign and malignant tumors in the liver.

However, several clinical trials are currently underway to assess a type of therapy that inhibits a DNA repair enzyme known as PARP in tumors with HRD,» said Heeke.

In the new study, scientists built upon previous discoveries that a safe, non-reproducing vaccine strain of T. gondii could cure mice of several types of solid tumors, and identified which parasite proteins and which immunological pathways are required to break immune tolerance.

The combination was significantly toxic to pancreatic cancer cells and disrupted tumor growth and extended survival in several types of advanced pancreatic cancer mouse models.

It also may have helped several others by boosting the power of a new type of cancer drug that uses a different mechanism to unleash an immune attack on the tumor.

VIC - 008 is a fusion protein combining an immune - activating protein from the tuberculosis bacteria with a small antibody fragment targeting mesothelin, a protein expressed in several types of tumor — including mesothelioma, pancreatic and ovarian cancer.

In the case of several major tumor types, the collagen matrix plays a critical role, Eliceiri says.

Scientists have known that LPA is secreted by many types of cancer cells, appears to promote the growth and spread of tumor cells, and that immune cells known as CD - 8 «killer» T cells have several receptors for LPA.

Dr. Eng and team create scoring system to facilitate identifying individuals to be referred to PTEN gene testing Researchers have discovered a method for more precise identification of individuals who should undergo testing for genetic mutations of the tumor suppressor gene PTEN, which associates with a variety of conditions including several types of cancers.

Recently, some other cytokines (such as tumor necrosis factor) or chemical drugs were also found to up - regulate several IFN - inducible gene family members (including RIG - G) through production of type I IFNs (37, 38), further indicating that the induction of RIG - G by ATRA in NB4 cells was tightly related with an IFNα autocrine pathway.

In a study published recently in Cell, researchers at the University of São Paulo's Ribeirão Preto Medical School (FMRP - USP) in Brazil and collaborators in several other countries describe a method that objectively measures the degree of similarity between tumor samples and pluripotent stem cells (cells that can differentiate into nearly any type of tissue in the body).

Important features of XMRV biology include (1) tropism for a variety of cell lines, including prostate cancer DU145 and LNCaP cells [27], [43], [48], and human neural cell types [57], (2) adaptations that promote growth in prostate epithelium and human - derived prostate cancer cell lines including an androgen response element in the promoter region [58] and downregulation of APOBEC3G [59], and (3) cellular effects with potential oncogenic properties including increased tumor aggressiveness mediated by downregulation of p27 [60] and differential regulation of several microRNAs [61].

We also found that several carriage strains had lost their type IV pili and that this loss correlated with reduced tumor necrosis factor alpha (TNF - α) expression when cultured with epithelial cells.

A neuroendocrine tumor can be one of several types of tumors, some cancerous and others benign, according to the National Cancer Institute.

Also included are people who recovered from tumors, several types of cancer, and infertility.

Magnolia (honokiol) reduced tumors in several types of cancers.

But because metformin may stem cancer through several different channels — by lowering insulin, directly slowing tumor growth, or promoting suicide by cancer cells — it could potentially prove useful in many types of cancer.

While genetics and environmental factors can play a role in the disease's development, other variables such as toxins, radiation, and tumor viruses, as well as hormones can also be responsible for causing several types of cancer.

Renal disease and several types of malignant tumors are the worst worries in this breed.

A fatty tumor (or lipoma) in dogs is one of several different types of skin tumors.

Ferrets are prone to several types of tumors.

Several treatments can be minimally invasive; the least invasive option may differ from dog to dog depending on the type of tumor the dog has.

Clinically, skin tumors resemble several other types of tumor so definitive diagnosis relies upon microscopic examination of tissue by cytology or histopathology.

There are several other types including mast cell tumors and lymphoma (see below).

Several types of testicular cancer exist; two thirds of testicular tumor cases involve malignant growths.

Tumors such as the case of several benign types of tumors which are referred to as being encapsulated, are candidates for a surgical appTumors such as the case of several benign types of tumors which are referred to as being encapsulated, are candidates for a surgical apptumors which are referred to as being encapsulated, are candidates for a surgical approach.

The use of targeting antibodies against vascular endothelial growth factor (VEGF), a protein that promotes tumor growth and spread, plus chemotherapy has prolonged disease free survival in several different tumor types in man.

Prognosis is influenced by several factors, including how big the tumor is, where it is within the brain, the type of brain tumor and the type of treatment.

Her work involves lymphoma, melanoma, mammary and other types of cancer and canine tumors, and it has been funded several times by the American Kennel Club and the National Institutes for Health.

There are several other more unusual tumor types that may be seen in this area such as the suprasellar germ cell tumor.

This type of tumor can originate in several areas with the most common sites being the spleen, heart, skin, and liver.

The outcome for patients with malignant mammary gland tumors depends on several factors including tumor type, histologic grade (appearance of the tumor cells under the microscope and how similar or dissimilar they are to normal tissues), tumor size, and tumor stage (presence of regional and distant metastasis).

My husband had a brain tumor several years ago (and by all accounts should have died, Praise the Lord he is still alive) and they don't know much about the type of tumor but possibly it grew at such a fast rate due to aspartame.